Cargando…
Privacy-Protecting, Reliable Response Data Discovery Using COVID-19 Patient Observations
There is an urgent need to answer questions related to COVID-19’s clinical course and associations with underlying conditions and health outcomes. Multi-center data are necessary to generate reliable answers, but centralizing data in a single repository is not always possible. Using a privacy-protec...
Autores principales: | , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523159/ https://www.ncbi.nlm.nih.gov/pubmed/32995818 http://dx.doi.org/10.1101/2020.09.21.20196220 |
_version_ | 1783588336699441152 |
---|---|
author | Kim, Jihoon Neumann, Larissa Paul, Paulina Aratow, Michael Bell, Douglas S. Doctor, Jason N. Hinske, Ludwig C. Jiang, Xiaoqian Kim, Katherine K. Matheny, Michael E. Meeker, Daniella Pletcher, Mark J. Schilling, Lisa M. SooHoo, Spencer Xu, Hua Zheng, Kai Ohno-Machado, Lucila |
author_facet | Kim, Jihoon Neumann, Larissa Paul, Paulina Aratow, Michael Bell, Douglas S. Doctor, Jason N. Hinske, Ludwig C. Jiang, Xiaoqian Kim, Katherine K. Matheny, Michael E. Meeker, Daniella Pletcher, Mark J. Schilling, Lisa M. SooHoo, Spencer Xu, Hua Zheng, Kai Ohno-Machado, Lucila |
author_sort | Kim, Jihoon |
collection | PubMed |
description | There is an urgent need to answer questions related to COVID-19’s clinical course and associations with underlying conditions and health outcomes. Multi-center data are necessary to generate reliable answers, but centralizing data in a single repository is not always possible. Using a privacy-protecting strategy, we launched a public Questions & Answers web portal (https://covid19questions.org) with analyses of comorbidities, medications and laboratory tests using data from 202 hospitals (59,074 COVID-19 patients) in the USA and Germany. We find, for example, that 8.6% of hospitalizations in which the patient was not admitted to the ICU resulted in the patient returning to the hospital within seven days from discharge and that, when adjusted for age, mortality for hospitalized patients was not significantly different by gender or ethnicity. |
format | Online Article Text |
id | pubmed-7523159 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Cold Spring Harbor Laboratory |
record_format | MEDLINE/PubMed |
spelling | pubmed-75231592020-09-30 Privacy-Protecting, Reliable Response Data Discovery Using COVID-19 Patient Observations Kim, Jihoon Neumann, Larissa Paul, Paulina Aratow, Michael Bell, Douglas S. Doctor, Jason N. Hinske, Ludwig C. Jiang, Xiaoqian Kim, Katherine K. Matheny, Michael E. Meeker, Daniella Pletcher, Mark J. Schilling, Lisa M. SooHoo, Spencer Xu, Hua Zheng, Kai Ohno-Machado, Lucila medRxiv Article There is an urgent need to answer questions related to COVID-19’s clinical course and associations with underlying conditions and health outcomes. Multi-center data are necessary to generate reliable answers, but centralizing data in a single repository is not always possible. Using a privacy-protecting strategy, we launched a public Questions & Answers web portal (https://covid19questions.org) with analyses of comorbidities, medications and laboratory tests using data from 202 hospitals (59,074 COVID-19 patients) in the USA and Germany. We find, for example, that 8.6% of hospitalizations in which the patient was not admitted to the ICU resulted in the patient returning to the hospital within seven days from discharge and that, when adjusted for age, mortality for hospitalized patients was not significantly different by gender or ethnicity. Cold Spring Harbor Laboratory 2020-09-23 /pmc/articles/PMC7523159/ /pubmed/32995818 http://dx.doi.org/10.1101/2020.09.21.20196220 Text en http://creativecommons.org/licenses/by-nc-nd/4.0/It is made available under a CC-BY-NC-ND 4.0 International license (http://creativecommons.org/licenses/by-nc-nd/4.0/) . |
spellingShingle | Article Kim, Jihoon Neumann, Larissa Paul, Paulina Aratow, Michael Bell, Douglas S. Doctor, Jason N. Hinske, Ludwig C. Jiang, Xiaoqian Kim, Katherine K. Matheny, Michael E. Meeker, Daniella Pletcher, Mark J. Schilling, Lisa M. SooHoo, Spencer Xu, Hua Zheng, Kai Ohno-Machado, Lucila Privacy-Protecting, Reliable Response Data Discovery Using COVID-19 Patient Observations |
title | Privacy-Protecting, Reliable Response Data Discovery Using COVID-19 Patient Observations |
title_full | Privacy-Protecting, Reliable Response Data Discovery Using COVID-19 Patient Observations |
title_fullStr | Privacy-Protecting, Reliable Response Data Discovery Using COVID-19 Patient Observations |
title_full_unstemmed | Privacy-Protecting, Reliable Response Data Discovery Using COVID-19 Patient Observations |
title_short | Privacy-Protecting, Reliable Response Data Discovery Using COVID-19 Patient Observations |
title_sort | privacy-protecting, reliable response data discovery using covid-19 patient observations |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523159/ https://www.ncbi.nlm.nih.gov/pubmed/32995818 http://dx.doi.org/10.1101/2020.09.21.20196220 |
work_keys_str_mv | AT kimjihoon privacyprotectingreliableresponsedatadiscoveryusingcovid19patientobservations AT neumannlarissa privacyprotectingreliableresponsedatadiscoveryusingcovid19patientobservations AT paulpaulina privacyprotectingreliableresponsedatadiscoveryusingcovid19patientobservations AT aratowmichael privacyprotectingreliableresponsedatadiscoveryusingcovid19patientobservations AT belldouglass privacyprotectingreliableresponsedatadiscoveryusingcovid19patientobservations AT doctorjasonn privacyprotectingreliableresponsedatadiscoveryusingcovid19patientobservations AT hinskeludwigc privacyprotectingreliableresponsedatadiscoveryusingcovid19patientobservations AT jiangxiaoqian privacyprotectingreliableresponsedatadiscoveryusingcovid19patientobservations AT kimkatherinek privacyprotectingreliableresponsedatadiscoveryusingcovid19patientobservations AT mathenymichaele privacyprotectingreliableresponsedatadiscoveryusingcovid19patientobservations AT meekerdaniella privacyprotectingreliableresponsedatadiscoveryusingcovid19patientobservations AT pletchermarkj privacyprotectingreliableresponsedatadiscoveryusingcovid19patientobservations AT schillinglisam privacyprotectingreliableresponsedatadiscoveryusingcovid19patientobservations AT soohoospencer privacyprotectingreliableresponsedatadiscoveryusingcovid19patientobservations AT xuhua privacyprotectingreliableresponsedatadiscoveryusingcovid19patientobservations AT zhengkai privacyprotectingreliableresponsedatadiscoveryusingcovid19patientobservations AT ohnomachadolucila privacyprotectingreliableresponsedatadiscoveryusingcovid19patientobservations |