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Privacy-Protecting, Reliable Response Data Discovery Using COVID-19 Patient Observations

There is an urgent need to answer questions related to COVID-19’s clinical course and associations with underlying conditions and health outcomes. Multi-center data are necessary to generate reliable answers, but centralizing data in a single repository is not always possible. Using a privacy-protec...

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Autores principales: Kim, Jihoon, Neumann, Larissa, Paul, Paulina, Aratow, Michael, Bell, Douglas S., Doctor, Jason N., Hinske, Ludwig C., Jiang, Xiaoqian, Kim, Katherine K., Matheny, Michael E., Meeker, Daniella, Pletcher, Mark J., Schilling, Lisa M., SooHoo, Spencer, Xu, Hua, Zheng, Kai, Ohno-Machado, Lucila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523159/
https://www.ncbi.nlm.nih.gov/pubmed/32995818
http://dx.doi.org/10.1101/2020.09.21.20196220
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author Kim, Jihoon
Neumann, Larissa
Paul, Paulina
Aratow, Michael
Bell, Douglas S.
Doctor, Jason N.
Hinske, Ludwig C.
Jiang, Xiaoqian
Kim, Katherine K.
Matheny, Michael E.
Meeker, Daniella
Pletcher, Mark J.
Schilling, Lisa M.
SooHoo, Spencer
Xu, Hua
Zheng, Kai
Ohno-Machado, Lucila
author_facet Kim, Jihoon
Neumann, Larissa
Paul, Paulina
Aratow, Michael
Bell, Douglas S.
Doctor, Jason N.
Hinske, Ludwig C.
Jiang, Xiaoqian
Kim, Katherine K.
Matheny, Michael E.
Meeker, Daniella
Pletcher, Mark J.
Schilling, Lisa M.
SooHoo, Spencer
Xu, Hua
Zheng, Kai
Ohno-Machado, Lucila
author_sort Kim, Jihoon
collection PubMed
description There is an urgent need to answer questions related to COVID-19’s clinical course and associations with underlying conditions and health outcomes. Multi-center data are necessary to generate reliable answers, but centralizing data in a single repository is not always possible. Using a privacy-protecting strategy, we launched a public Questions & Answers web portal (https://covid19questions.org) with analyses of comorbidities, medications and laboratory tests using data from 202 hospitals (59,074 COVID-19 patients) in the USA and Germany. We find, for example, that 8.6% of hospitalizations in which the patient was not admitted to the ICU resulted in the patient returning to the hospital within seven days from discharge and that, when adjusted for age, mortality for hospitalized patients was not significantly different by gender or ethnicity.
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spelling pubmed-75231592020-09-30 Privacy-Protecting, Reliable Response Data Discovery Using COVID-19 Patient Observations Kim, Jihoon Neumann, Larissa Paul, Paulina Aratow, Michael Bell, Douglas S. Doctor, Jason N. Hinske, Ludwig C. Jiang, Xiaoqian Kim, Katherine K. Matheny, Michael E. Meeker, Daniella Pletcher, Mark J. Schilling, Lisa M. SooHoo, Spencer Xu, Hua Zheng, Kai Ohno-Machado, Lucila medRxiv Article There is an urgent need to answer questions related to COVID-19’s clinical course and associations with underlying conditions and health outcomes. Multi-center data are necessary to generate reliable answers, but centralizing data in a single repository is not always possible. Using a privacy-protecting strategy, we launched a public Questions & Answers web portal (https://covid19questions.org) with analyses of comorbidities, medications and laboratory tests using data from 202 hospitals (59,074 COVID-19 patients) in the USA and Germany. We find, for example, that 8.6% of hospitalizations in which the patient was not admitted to the ICU resulted in the patient returning to the hospital within seven days from discharge and that, when adjusted for age, mortality for hospitalized patients was not significantly different by gender or ethnicity. Cold Spring Harbor Laboratory 2020-09-23 /pmc/articles/PMC7523159/ /pubmed/32995818 http://dx.doi.org/10.1101/2020.09.21.20196220 Text en http://creativecommons.org/licenses/by-nc-nd/4.0/It is made available under a CC-BY-NC-ND 4.0 International license (http://creativecommons.org/licenses/by-nc-nd/4.0/) .
spellingShingle Article
Kim, Jihoon
Neumann, Larissa
Paul, Paulina
Aratow, Michael
Bell, Douglas S.
Doctor, Jason N.
Hinske, Ludwig C.
Jiang, Xiaoqian
Kim, Katherine K.
Matheny, Michael E.
Meeker, Daniella
Pletcher, Mark J.
Schilling, Lisa M.
SooHoo, Spencer
Xu, Hua
Zheng, Kai
Ohno-Machado, Lucila
Privacy-Protecting, Reliable Response Data Discovery Using COVID-19 Patient Observations
title Privacy-Protecting, Reliable Response Data Discovery Using COVID-19 Patient Observations
title_full Privacy-Protecting, Reliable Response Data Discovery Using COVID-19 Patient Observations
title_fullStr Privacy-Protecting, Reliable Response Data Discovery Using COVID-19 Patient Observations
title_full_unstemmed Privacy-Protecting, Reliable Response Data Discovery Using COVID-19 Patient Observations
title_short Privacy-Protecting, Reliable Response Data Discovery Using COVID-19 Patient Observations
title_sort privacy-protecting, reliable response data discovery using covid-19 patient observations
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523159/
https://www.ncbi.nlm.nih.gov/pubmed/32995818
http://dx.doi.org/10.1101/2020.09.21.20196220
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