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Use of the Reversible Myogenic to Lipogenic Transdifferentiation Switch for the Design of Pre-clinical Drug Screening in Idiopathic Pulmonary Fibrosis

Idiopathic Pulmonary Fibrosis (IPF) is an end-stage lung disease characterized by excessive extracellular matrix (ECM) deposition from activated myofibroblasts (MYFs) and tissue scarring. Eventually leading to stiffening of the lung, capable of assuming only limited gas exchange function. So far two...

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Detalles Bibliográficos
Autores principales:	Lingampally, Arun, Jones, Matthew R., Bagari, Shirisha, Chen, Chengshui, Rivetti, Stefano, Bellusci, Saverio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523217/ https://www.ncbi.nlm.nih.gov/pubmed/33042971 http://dx.doi.org/10.3389/fbioe.2020.569865

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