Curcumin derivative C212 inhibits Hsp90 and eliminates both growing and quiescent leukemia cells in deep dormancy

BACKGROUND: Relapsed leukemia following initial therapeutic response and remission is difficult to treat and causes high patient mortality. Leukemia relapse is due to residual quiescent leukemia cells that escape conventional therapies and later reemerge. Eliminating not only growing but quiescent l...

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Detalles Bibliográficos
Autores principales: Liu, Bi, Shen, Yunzhu, Huang, Huafang, Croce, Kimiko Della, Wu, Min, Fan, Yingjuan, Liu, Yang, Xu, Jianhua, Yao, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523331/
https://www.ncbi.nlm.nih.gov/pubmed/32993709
http://dx.doi.org/10.1186/s12964-020-00652-4

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