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Microparticles derived from human erythropoietin mRNA-transfected mesenchymal stem cells inhibit epithelial-to-mesenchymal transition and ameliorate renal interstitial fibrosis

BACKGROUND: Renal tubulointerstitial fibrosis (TIF) plays an important role in the progression of chronic kidney disease (CKD) and its pathogenesis involves epithelial-to-mesenchymal transition (EMT) upon renal injury. Recombinant human erythropoietin (rhEPO) has been shown to display novel cytoprot...

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Detalles Bibliográficos
Autores principales:	Lee, Mirae, Kim, Seok-hyung, Jhee, Jong Hyun, Kim, Tae Yeon, Choi, Hoon Young, Kim, Hyung Jong, Park, Hyeong Cheon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523343/ https://www.ncbi.nlm.nih.gov/pubmed/32993806 http://dx.doi.org/10.1186/s13287-020-01932-z

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