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BRAF Alteration in Central and Peripheral Nervous System Tumors

BRAF (alternately referred to as v-raf murine sarcoma viral oncogene homolog B1) is a proto-oncogene involved in the mitogen-activated protein kinase (MAPK) pathway. BRAF alterations are most commonly missense mutations or aberrant fusions. These mutations are observed in numerous primary central ne...

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Detalles Bibliográficos
Autores principales: Srinivasa, Komal, Cross, Kevin A., Dahiya, Sonika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523461/
https://www.ncbi.nlm.nih.gov/pubmed/33042847
http://dx.doi.org/10.3389/fonc.2020.574974