Cargando…

Hematopoietic Cell Kinase (HCK) Is Essential for NLRP3 Inflammasome Activation and Lipopolysaccharide-Induced Inflammatory Response In Vivo

Activation of the NLRP3 inflammasome results in caspase 1 cleavage, which subsequently leads to IL-1β and IL-18 secretion, as well as pyroptosis, and aberrant activation of the inflammasome is involved in several diseases such as type 2 diabetes, atherosclerosis, multiple sclerosis, Parkinson’s dise...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kong, Xiangxi, Liao, Yajin, Zhou, Lujun, Zhang, Ying, Cheng, Jinbo, Yuan, Zengqiang, Wang, Shukun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523510/ https://www.ncbi.nlm.nih.gov/pubmed/33041826 http://dx.doi.org/10.3389/fphar.2020.581011

Ejemplares similares

The XPO1 Inhibitor KPT-8602 Ameliorates Parkinson’s Disease by Inhibiting the NF-κB/NLRP3 Pathway
por: Liu, Shuhan, et al.
Publicado: (2022)

Stress-induced NLRP3 inflammasome activation negatively regulates fear memory in mice
por: Dong, Yuan, et al.
Publicado: (2020)

Hematopoietic cell kinase (HCK) as a therapeutic target in immune and cancer cells
por: Poh, Ashleigh R., et al.
Publicado: (2015)

Neurodegenerative Disease and the NLRP3 Inflammasome
por: Holbrook, Jonathan A., et al.
Publicado: (2021)

Selective targeting of the inactive state of hematopoietic cell kinase (Hck) with a stable curcumin derivative
por: Chakraborty, Manas Pratim, et al.
Publicado: (2021)

The Essential Oil of Artemisia argyi H.Lév. and Vaniot Attenuates NLRP3 Inflammasome Activation in THP-1 Cells
por: Chen, Pengxiao, et al.
Publicado: (2021)

The role of NLRP3 inflammasome in hepatocellular carcinoma
por: Zhao, Huijie, et al.
Publicado: (2023)

Amplified RLR signaling activation through an interferon-stimulated gene-endoplasmic reticulum stress-mitochondrial calcium uniporter protein loop
por: Cheng, Jinbo, et al.
Publicado: (2016)

Pinelliae rhizoma alleviated acute lung injury induced by lipopolysaccharide via suppressing endoplasmic reticulum stress-mediated NLRP3 inflammasome
por: Wang, Ning-ning, et al.
Publicado: (2022)

Lipopolysaccharide (LPS)-induced Macrophage Activation and Signal Transduction in the Absence of Src-Family Kinases Hck, Fgr, and Lyn
por: Meng, Fanying, et al.
Publicado: (1997)

Dihydrotanshinone I Specifically Inhibits NLRP3 Inflammasome Activation and Protects Against Septic Shock In Vivo
por: Wei, Ziying, et al.
Publicado: (2021)

NLRP3 inflammasome and its inhibitors: a review
por: Shao, Bo-Zong, et al.
Publicado: (2015)

Activation of Platelet NLRP3 Inflammasome in Crohn’s Disease
por: Zhang, Ge, et al.
Publicado: (2021)

The SH3 regulatory domain of the hematopoietic cell kinase Hck binds ELMO via its polyproline motif
por: Awad, Rida, et al.
Publicado: (2015)

Natural Products that Target the NLRP3 Inflammasome to Treat Fibrosis
por: Ding, Nan, et al.
Publicado: (2020)

MicroRNA Post-transcriptional Regulation of the NLRP3 Inflammasome in Immunopathologies
por: Tezcan, Gulcin, et al.
Publicado: (2019)

Role of NLRP3 Inflammasome in Lupus Nephritis and Therapeutic Targeting by Phytochemicals
por: Wu, Dantong, et al.
Publicado: (2021)

The Role of NLRP3 Inflammasome in Alzheimer’s Disease and Potential Therapeutic Targets
por: Liang, Tao, et al.
Publicado: (2022)

Pharmacological intervention of curcumin via the NLRP3 inflammasome in ischemic stroke
por: Du, Xiaoxue, et al.
Publicado: (2023)

Dlg1 Knockout Inhibits Microglial Activation and Alleviates Lipopolysaccharide-Induced Depression-Like Behavior in Mice
por: Peng, Zhixin, et al.
Publicado: (2021)

Hematopoietic Cell Kinase (HCK) Is a Player of the Crosstalk Between Hematopoietic Cells and Bone Marrow Niche Through CXCL12/CXCR4 Axis
por: Roversi, Fernanda Marconi, et al.
Publicado: (2021)

Amentoflavone Affects Epileptogenesis and Exerts Neuroprotective Effects by Inhibiting NLRP3 Inflammasome
por: Rong, Shikuo, et al.
Publicado: (2019)

Targeting NLRP3 Inflammasome in Translational Treatment of Nervous System Diseases: An Update
por: Yu, Qingying, et al.
Publicado: (2021)

Plant-derived bioactive compounds regulate the NLRP3 inflammasome to treat NAFLD
por: Huang, Qian, et al.
Publicado: (2022)

Neuroprotective Effects of Qingnao Dripping Pills Against Cerebral Ischemia via Inhibiting NLRP3 Inflammasome Signaling Pathway: In Vivo and In Vitro
por: Fu, Chen, et al.
Publicado: (2020)

Regulation of p73 by Hck through kinase-dependent and independent mechanisms
por: Paliwal, Preeti, et al.
Publicado: (2007)

Norcantharidin ameliorates estrogen deficient-mediated bone loss by attenuating the activation of extracellular signal-regulated kinase/ROS/NLRP3 inflammasome signaling
por: Yang, Guang, et al.
Publicado: (2022)

Dexmedetomidine Enhances Autophagy via α2-AR/AMPK/mTOR Pathway to Inhibit the Activation of NLRP3 Inflammasome and Subsequently Alleviates Lipopolysaccharide-Induced Acute Kidney Injury
por: Yang, Tianyuan, et al.
Publicado: (2020)

Yupingfeng San Inhibits NLRP3 Inflammasome to Attenuate the Inflammatory Response in Asthma Mice
por: Liu, Xue, et al.
Publicado: (2017)

Lack of the Nlrp3 Inflammasome Improves Mice Recovery Following Traumatic Brain Injury
por: Irrera, Natasha, et al.
Publicado: (2017)

Fisetin Attenuates Diabetic Nephropathy-Induced Podocyte Injury by Inhibiting NLRP3 Inflammasome
por: Dong, Wenmin, et al.
Publicado: (2022)

Natural Products as a Novel Therapeutic Strategy for NLRP3 Inflammasome-Mediated Gout
por: Lee, Jun Ho, et al.
Publicado: (2022)

Pharmacological effects of Chinese medicine modulating NLRP3 inflammasomes in fatty liver treatment
por: Liu, Tingting, et al.
Publicado: (2022)

The NLRP3 inflammasome is involved in resident intruder paradigm-induced aggressive behaviors in mice
por: Yu, Qingying, et al.
Publicado: (2023)

AICAR, an AMP-Activated Protein Kinase Activator, Ameliorates Acute Pancreatitis-Associated Liver Injury Partially Through Nrf2-Mediated Antioxidant Effects and Inhibition of NLRP3 Inflammasome Activation
por: Kong, Lijun, et al.
Publicado: (2021)

Gallic acid ameliorates dextran sulfate sodium-induced ulcerative colitis in mice via inhibiting NLRP3 inflammasome
por: Yu, Tian-Yuan, et al.
Publicado: (2023)

Inflammatory-Dependent Bidirectional Effect of Bile Acids on NLRP3 Inflammasome and Its Role in Ameliorating CPT-11-Induced Colitis
por: Liao, Chuyao, et al.
Publicado: (2022)

The SRC-family tyrosine kinase HCK shapes the landscape of SKAP2 interactome
por: Bureau, Jean-François, et al.
Publicado: (2018)

Scutellarin Suppresses NLRP3 Inflammasome Activation in Macrophages and Protects Mice against Bacterial Sepsis
por: Liu, Yi, et al.
Publicado: (2018)

CRP-Induced NLRP3 Inflammasome Activation Increases LDL Transcytosis Across Endothelial Cells
por: Bian, Fang, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_rcvg63g5lfh4jkktibdaeo5c76