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Bronchiectasis with secondary pulmonary infection in a child: A case report

RATIONALE: Although bronchiectasis is conventionally considered a chronic pulmonary disease of adulthood, knowledge of pediatric bronchiectasis not related to cystic fibrosis started to emerge. Limited information in this field is available and the management is based on expert opinion. PATIENT CONC...

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Autores principales: Zhu, Ting, Gu, Haoxiang, Vinturache, Angela, Ding, Guodong, Lu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523858/
https://www.ncbi.nlm.nih.gov/pubmed/32991486
http://dx.doi.org/10.1097/MD.0000000000022475
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author Zhu, Ting
Gu, Haoxiang
Vinturache, Angela
Ding, Guodong
Lu, Min
author_facet Zhu, Ting
Gu, Haoxiang
Vinturache, Angela
Ding, Guodong
Lu, Min
author_sort Zhu, Ting
collection PubMed
description RATIONALE: Although bronchiectasis is conventionally considered a chronic pulmonary disease of adulthood, knowledge of pediatric bronchiectasis not related to cystic fibrosis started to emerge. Limited information in this field is available and the management is based on expert opinion. PATIENT CONCERNS: An 8-year-old girl admitted for 7 days history of wet cough, purulent fetid sputum, shortness of breath and low-grade fever. The wet cough has presented for the past 4 years, during which she had frequent hospitalization for recurrent lower respiratory tract infections. DIAGNOSIS: Chest high-resolution computerized tomography revealed diffuse bronchial dilations accompanied by inflammation in the bilateral lung fields. Microbiologic investigation for bronchoalveolar lavage fluid was positive for Pseudomonas aeruginosa. INTERVENTIONS: With a working diagnosis of bronchiectasis with secondary pulmonary infection, sensitive cefoperazone-sulbactam was administrated for 14 days with gradual improvement of clinical symptoms. Bronchoscopy washing substantially soothed the symptoms, reducing the cough and sputum volumes. OUTCOMES: The child was discharged after 14 days, and treated on long-term prophylactic antibiotic use (amoxicillin-clavulanic acid, 20 mg/kg/d, ≥ 4 weeks). LESSONS: Although bronchiectasisis are condition in childhood, the diagnosis is suspected in children with persistent wet or productive cough, and should be confirmed by a chest high-resolution computerized tomography scan. Antibiotics and airway clearance techniques represent the milestones of bronchiectasis management although there are only a few guidelines in children.
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spelling pubmed-75238582020-10-14 Bronchiectasis with secondary pulmonary infection in a child: A case report Zhu, Ting Gu, Haoxiang Vinturache, Angela Ding, Guodong Lu, Min Medicine (Baltimore) 6200 RATIONALE: Although bronchiectasis is conventionally considered a chronic pulmonary disease of adulthood, knowledge of pediatric bronchiectasis not related to cystic fibrosis started to emerge. Limited information in this field is available and the management is based on expert opinion. PATIENT CONCERNS: An 8-year-old girl admitted for 7 days history of wet cough, purulent fetid sputum, shortness of breath and low-grade fever. The wet cough has presented for the past 4 years, during which she had frequent hospitalization for recurrent lower respiratory tract infections. DIAGNOSIS: Chest high-resolution computerized tomography revealed diffuse bronchial dilations accompanied by inflammation in the bilateral lung fields. Microbiologic investigation for bronchoalveolar lavage fluid was positive for Pseudomonas aeruginosa. INTERVENTIONS: With a working diagnosis of bronchiectasis with secondary pulmonary infection, sensitive cefoperazone-sulbactam was administrated for 14 days with gradual improvement of clinical symptoms. Bronchoscopy washing substantially soothed the symptoms, reducing the cough and sputum volumes. OUTCOMES: The child was discharged after 14 days, and treated on long-term prophylactic antibiotic use (amoxicillin-clavulanic acid, 20 mg/kg/d, ≥ 4 weeks). LESSONS: Although bronchiectasisis are condition in childhood, the diagnosis is suspected in children with persistent wet or productive cough, and should be confirmed by a chest high-resolution computerized tomography scan. Antibiotics and airway clearance techniques represent the milestones of bronchiectasis management although there are only a few guidelines in children. Lippincott Williams & Wilkins 2020-09-25 /pmc/articles/PMC7523858/ /pubmed/32991486 http://dx.doi.org/10.1097/MD.0000000000022475 Text en Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0
spellingShingle 6200
Zhu, Ting
Gu, Haoxiang
Vinturache, Angela
Ding, Guodong
Lu, Min
Bronchiectasis with secondary pulmonary infection in a child: A case report
title Bronchiectasis with secondary pulmonary infection in a child: A case report
title_full Bronchiectasis with secondary pulmonary infection in a child: A case report
title_fullStr Bronchiectasis with secondary pulmonary infection in a child: A case report
title_full_unstemmed Bronchiectasis with secondary pulmonary infection in a child: A case report
title_short Bronchiectasis with secondary pulmonary infection in a child: A case report
title_sort bronchiectasis with secondary pulmonary infection in a child: a case report
topic 6200
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523858/
https://www.ncbi.nlm.nih.gov/pubmed/32991486
http://dx.doi.org/10.1097/MD.0000000000022475
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