Cargando…
STAT1 deficiency predisposes to spontaneous otitis media
Signal transducer and activator of transcription 1 (STAT1) is known to be an important player in inflammatory responses. STAT1 as a transcription factor regulates the expression of multiple proinflammatory genes. Inflammatory response is one of the common effects of ototoxicity. Our group reported t...
Autores principales: | Bodmer, Daniel, Kern, Peter, Bächinger, David, Monge Naldi, Arianne, Levano Huaman, Soledad |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523960/ https://www.ncbi.nlm.nih.gov/pubmed/32991625 http://dx.doi.org/10.1371/journal.pone.0239952 |
Ejemplares similares
-
Functional and morphological analysis of different aminoglycoside treatment regimens inducing hearing loss in mice
por: Horvath, Lukas, et al.
Publicado: (2019) -
Sesn2/AMPK/mTOR signaling mediates balance between survival and apoptosis in sensory hair cells under stress
por: Bodmer, Daniel, et al.
Publicado: (2017) -
All Akt Isoforms (Akt1, Akt2, Akt3) Are Involved in Normal Hearing, but Only Akt2 and Akt3 Are Involved in Auditory Hair Cell Survival in the Mammalian Inner Ear
por: Brand, Yves, et al.
Publicado: (2015) -
Sesn2 gene ablation enhances susceptibility to gentamicin-induced hair cell death via modulation of AMPK/mTOR signaling
por: Ebnoether, Eliane, et al.
Publicado: (2017) -
Loss of STAT1 protects hair cells from ototoxicity through modulation of STAT3, c-Jun, Akt, and autophagy factors
por: Levano, S, et al.
Publicado: (2015)