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Innate, non-cytolytic CD8(+) T cell-mediated suppression of HIV replication by MHC-independent inhibition of virus transcription

MHC-I-restricted, virus-specific cytotoxic CD8(+) T cells (CTLs) may control human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) replication via the recognition and killing of productively infected CD4(+) T cells. Several studies in SIV-infected macaques suggest that CD8(+) T...

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Detalles Bibliográficos
Autores principales:	Zanoni, Michelle, Palesch, David, Pinacchio, Claudia, Statzu, Maura, Tharp, Gregory K., Paiardini, Mirko, Chahroudi, Ann, Bosinger, Steven E., Yoon, Jack, Cox, Bryan, Silvestri, Guido, Kulpa, Deanna A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523993/ https://www.ncbi.nlm.nih.gov/pubmed/32941545 http://dx.doi.org/10.1371/journal.ppat.1008821

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