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Giant cell myocarditis in an older patient – reassessing the threshold for endomyocardial biopsy

Giant cell myocarditis is a rare form of autoimmune myocarditis with high morbidity and mortality that affects mainly middle‐aged adults. We report a case study of a 70‐year‐old man on chronic immunosuppression who presented with sustained ventricular tachycardia and symptoms of acute systolic heart...

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Detalles Bibliográficos
Autores principales: Dusík, Milan, Daud, Anees, Šmíd, Ondřej, Havránek, Štěpán, Vítková, Ivana, Revelo, Monica Patricia, Stehlik, Josef, Linhart, Aleš, Bělohlávek, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524070/
https://www.ncbi.nlm.nih.gov/pubmed/32644298
http://dx.doi.org/10.1002/ehf2.12756
Descripción
Sumario:Giant cell myocarditis is a rare form of autoimmune myocarditis with high morbidity and mortality that affects mainly middle‐aged adults. We report a case study of a 70‐year‐old man on chronic immunosuppression who presented with sustained ventricular tachycardia and symptoms of acute systolic heart failure, both with poor response to standard measures. A decision to pursue endomyocardial biopsy established the diagnosis of GCM and lead to initiation of immunosuppressive therapy and a favourable outcome. Our case illustrates that a low threshold for endomyocardial biopsy in new onset heart failure can lead to actionable information even in patients of advanced age.