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Giant cell myocarditis in an older patient – reassessing the threshold for endomyocardial biopsy

Giant cell myocarditis is a rare form of autoimmune myocarditis with high morbidity and mortality that affects mainly middle‐aged adults. We report a case study of a 70‐year‐old man on chronic immunosuppression who presented with sustained ventricular tachycardia and symptoms of acute systolic heart...

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Autores principales: Dusík, Milan, Daud, Anees, Šmíd, Ondřej, Havránek, Štěpán, Vítková, Ivana, Revelo, Monica Patricia, Stehlik, Josef, Linhart, Aleš, Bělohlávek, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524070/
https://www.ncbi.nlm.nih.gov/pubmed/32644298
http://dx.doi.org/10.1002/ehf2.12756
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author Dusík, Milan
Daud, Anees
Šmíd, Ondřej
Havránek, Štěpán
Vítková, Ivana
Revelo, Monica Patricia
Stehlik, Josef
Linhart, Aleš
Bělohlávek, Jan
author_facet Dusík, Milan
Daud, Anees
Šmíd, Ondřej
Havránek, Štěpán
Vítková, Ivana
Revelo, Monica Patricia
Stehlik, Josef
Linhart, Aleš
Bělohlávek, Jan
author_sort Dusík, Milan
collection PubMed
description Giant cell myocarditis is a rare form of autoimmune myocarditis with high morbidity and mortality that affects mainly middle‐aged adults. We report a case study of a 70‐year‐old man on chronic immunosuppression who presented with sustained ventricular tachycardia and symptoms of acute systolic heart failure, both with poor response to standard measures. A decision to pursue endomyocardial biopsy established the diagnosis of GCM and lead to initiation of immunosuppressive therapy and a favourable outcome. Our case illustrates that a low threshold for endomyocardial biopsy in new onset heart failure can lead to actionable information even in patients of advanced age.
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spelling pubmed-75240702020-10-02 Giant cell myocarditis in an older patient – reassessing the threshold for endomyocardial biopsy Dusík, Milan Daud, Anees Šmíd, Ondřej Havránek, Štěpán Vítková, Ivana Revelo, Monica Patricia Stehlik, Josef Linhart, Aleš Bělohlávek, Jan ESC Heart Fail Case Report Giant cell myocarditis is a rare form of autoimmune myocarditis with high morbidity and mortality that affects mainly middle‐aged adults. We report a case study of a 70‐year‐old man on chronic immunosuppression who presented with sustained ventricular tachycardia and symptoms of acute systolic heart failure, both with poor response to standard measures. A decision to pursue endomyocardial biopsy established the diagnosis of GCM and lead to initiation of immunosuppressive therapy and a favourable outcome. Our case illustrates that a low threshold for endomyocardial biopsy in new onset heart failure can lead to actionable information even in patients of advanced age. John Wiley and Sons Inc. 2020-07-09 /pmc/articles/PMC7524070/ /pubmed/32644298 http://dx.doi.org/10.1002/ehf2.12756 Text en © 2020 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of the European Society of Cardiology This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Report
Dusík, Milan
Daud, Anees
Šmíd, Ondřej
Havránek, Štěpán
Vítková, Ivana
Revelo, Monica Patricia
Stehlik, Josef
Linhart, Aleš
Bělohlávek, Jan
Giant cell myocarditis in an older patient – reassessing the threshold for endomyocardial biopsy
title Giant cell myocarditis in an older patient – reassessing the threshold for endomyocardial biopsy
title_full Giant cell myocarditis in an older patient – reassessing the threshold for endomyocardial biopsy
title_fullStr Giant cell myocarditis in an older patient – reassessing the threshold for endomyocardial biopsy
title_full_unstemmed Giant cell myocarditis in an older patient – reassessing the threshold for endomyocardial biopsy
title_short Giant cell myocarditis in an older patient – reassessing the threshold for endomyocardial biopsy
title_sort giant cell myocarditis in an older patient – reassessing the threshold for endomyocardial biopsy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524070/
https://www.ncbi.nlm.nih.gov/pubmed/32644298
http://dx.doi.org/10.1002/ehf2.12756
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