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Oral delivery of Hyperimmune bovine serum antibodies against CS6-expressing enterotoxigenic Escherichia coli as a prophylactic against diarrhea

BACKGROUND: . Oral administration of bovine antibodies active against enterotoxigenic Escherichia coli (ETEC) have demonstrated safety and efficacy against diarrhea in human challenge trials. The efficacy of bovine serum immunoglobulins (BSIgG) against recombinant colonization factor CS6 or whole ce...

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Detalles Bibliográficos
Autores principales: Talaat, KR, Porter, CK, Bourgeois, AL, Lee, TK, Duplessis, CA, Maciel, M, Gutierrez, RL, DeNearing, B, Adjoodani, B, Adkinson, R, Testa, KJ, Feijoo, B, Alcala, AN, Brubaker, J, Beselman, A, Chakraborty, S, Sack, D, Halpern, J, Trop, S, Wu, H, Jiao, J, Sullivan, E, Riddle, MS, Joseph, SS, Poole, ST, Prouty, MG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524165/
https://www.ncbi.nlm.nih.gov/pubmed/32167011
http://dx.doi.org/10.1080/19490976.2020.1732852