Cargando…
Anti-Tumor Xanthones from Garcinia nujiangensis Suppress Proliferation, and Induce Apoptosis via PARP, PI3K/AKT/mTOR, and MAPK/ERK Signaling Pathways in Human Ovarian Cancers Cells
BACKGROUND: Ovarian cancer (OC) is a serious public health concern in the world. It is important to develop novel drugs to inhibit OC. PURPOSE: This study investigated the isolation, elucidation, efficiency, molecular docking, and pharmaceutical mechanisms of xanthones isolated from Garcinia nujiang...
Autores principales: | Tang, Zhongyan, Lu, Lihua, Xia, Zhengxiang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524179/ https://www.ncbi.nlm.nih.gov/pubmed/33061301 http://dx.doi.org/10.2147/DDDT.S258811 |
Ejemplares similares
-
The Roles of PI3K/AKT/mTOR and MAPK/ERK Signaling Pathways in Human Pheochromocytomas
por: Du, Juan, et al.
Publicado: (2016) -
Xanthones from the Pericarp of Garcinia mangostana
por: Yang, Renyue, et al.
Publicado: (2017) -
Apatinib induces apoptosis and autophagy via the PI3K/AKT/mTOR and MAPK/ERK signaling pathways in neuroblastoma
por: Yu, Xiying, et al.
Publicado: (2020) -
Cytotoxic Prenylated Xanthones from the Pericarps of Garcinia mangostana
por: Xu, Zeng, et al.
Publicado: (2014) -
Nujiangexathone A, a Novel Compound Derived from Garcinia nujiangensis, Induces Caspase-Dependent Apoptosis in Cervical Cancer through the ROS/JNK Pathway
por: Zhang, Li, et al.
Publicado: (2016)