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DPP-4 Inhibitor Linagliptin Ameliorates Oxidized LDL-Induced THP-1 Macrophage Foam Cell Formation and Inflammation

INTRODUCTION: Atherosclerosis is one of the major causes of cardiovascular diseases. Lipid uptake and accumulation in macrophages play a major role in atherosclerotic plaque formation from its initiation to advanced atheroma formation. The dipeptidyl peptidase-4 (DPP-4) inhibitor Linagliptin is comm...

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Detalles Bibliográficos
Autores principales:	Wang, Haoran, Li, Yue, Zhang, Xiaoliang, Xu, Zhonglin, Zhou, Jianzhong, Shang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524190/ https://www.ncbi.nlm.nih.gov/pubmed/33061298 http://dx.doi.org/10.2147/DDDT.S249846

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