Bile salt metabolism is not the only factor contributing to Clostridioides (Clostridium) difficile disease severity in the murine model of disease

Susceptibility of patients to antibiotic-associated C. difficile disease is intimately associated with specific changes to gut microbiome composition. In particular, loss of microbes that modify bile salt acids (BSA) play a central role; primary bile acids stimulate spore germination whilst secondar...

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Detalles Bibliográficos
Autores principales: Jukes, Caitlin A., Ijaz, Umer Zeeshan, Buckley, Anthony, Spencer, Janice, Irvine, June, Candlish, Denise, Li, Jia V., Marchesi, Julian R., Douce, Gillian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper/Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524298/
https://www.ncbi.nlm.nih.gov/pubmed/31793403
http://dx.doi.org/10.1080/19490976.2019.1678996

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