Pre-therapy fasting slows epithelial turnover and modulates the microbiota but fails to mitigate methotrexate-induced gastrointestinal mucositis

BACKGROUND: Recent findings by Tang et al. (2020) show dietary restriction (30%, 2 weeks) prevents methotrexate-induced mortality by modulation of the microbiota, specifically the expansion of Lactobacillus. While fundamentally insightful, upscaling this schedule is a major obstacle to clinical upta...

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Detalles Bibliográficos
Autores principales: Wardill, H. R., da Silva Ferreira, A. R., Lichtenberg Cloo, S., Havinga, R., Harmsen, H. J. M., Vermeij, W. P., Tissing, W. J. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524354/
https://www.ncbi.nlm.nih.gov/pubmed/32844722
http://dx.doi.org/10.1080/19490976.2020.1809332

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