Cargando…

Beneficial bacteria activate type-I interferon production via the intracellular cytosolic sensors STING and MAVS

Type-I interferon (IFN-I) cytokines are produced by immune cells in response to microbial infections, cancer and autoimmune diseases, and subsequently, trigger cytoprotective and antiviral responses through the activation of IFN-I stimulated genes (ISGs). The ability of intestinal microbiota to modu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gutierrez-Merino, Jorge, Isla, Beatriz, Combes, Theo, Martinez-Estrada, Fernando, Maluquer De Motes, Carlos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2020
Materias:	Research Paper/Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524384/ https://www.ncbi.nlm.nih.gov/pubmed/31941397 http://dx.doi.org/10.1080/19490976.2019.1707015

Ejemplares similares

The Pharmacologically Active Alkaloid Cryptolepine Activates a Type 1 Interferon Response That Is Independent of MAVS and STING Pathways
por: Domfeh, Seth A., et al.
Publicado: (2022)

Autophagy takes the STING out of DNA sensing
por: Maluquer de Motes, Carlos
Publicado: (2021)

Molecular Mechanisms of the Toll-Like Receptor, STING, MAVS, Inflammasome, and Interferon Pathways
por: Manes, Nathan P., et al.
Publicado: (2021)

Both STING and MAVS Fish Orthologs Contribute to the Induction of Interferon Mediated by RIG-I
por: Biacchesi, Stéphane, et al.
Publicado: (2012)

Vaccinia Virus Activation and Antagonism of Cytosolic DNA Sensing
por: El-Jesr, Misbah, et al.
Publicado: (2020)

Human Cancer Cells Sense Cytosolic Nucleic Acids Through the RIG-I–MAVS Pathway and cGAS–STING Pathway
por: Qiao, Yuan, et al.
Publicado: (2021)

Virulent Poxviruses Inhibit DNA Sensing by Preventing STING Activation
por: Georgana, Iliana, et al.
Publicado: (2018)

Autoimmunity gene IRGM suppresses cGAS‐STING and RIG‐I‐MAVS signaling to control interferon response
por: Jena, Kautilya Kumar, et al.
Publicado: (2020)

Human cytomegalovirus-encoded US9 targets MAVS and STING signaling to evade type I interferon immune responses
por: Choi, Hyun jin, et al.
Publicado: (2018)

Lactic acid Bacteria isolated from European badgers (Meles meles) reduce the viability and survival of Bacillus Calmette-Guerin (BCG) vaccine and influence the immune response to BCG in a human macrophage model
por: Stedman, Anna, et al.
Publicado: (2018)

Molecular evolutionary and structural analysis of the cytosolic DNA sensor cGAS and STING
por: Wu, Xiaomei, et al.
Publicado: (2014)

Cytosolic sensor STING in mucosal immunity: a master regulator of gut inflammation and carcinogenesis
por: Hu, Qiongyuan, et al.
Publicado: (2021)

A mathematic model to reveal delicate cross‐regulation between MAVS/STING, inflammasome and MyD88‐dependent type I interferon signalling
por: Cai, Chunmei, et al.
Publicado: (2020)

Research Note: Interactions among the MDA5, MAVS, and STING signaling pathways in chicken cells
por: Shin, Seung Pyo, et al.
Publicado: (2023)

STING-dependent cytosolic DNA sensor pathways regulate NKG2D ligand expression
por: Le Bert, Nina, et al.
Publicado: (2014)

Poxvirus cGAMP nucleases: Clues and mysteries from a stolen gene
por: Maluquer de Motes, Carlos
Publicado: (2021)

RIG-I/MAVS and STING signaling promote gut integrity during irradiation- and immune-mediated tissue injury
por: Fischer, Julius C., et al.
Publicado: (2017)

PPM1G restricts innate immune signaling mediated by STING and MAVS and is hijacked by KSHV for immune evasion
por: Yu, Kuai, et al.
Publicado: (2020)

Excavaciones arqueológicas en el cerro del Berrueco, Salamanca
por: Maluquer de Motes Nicolau, Juan
Publicado: (1958)

The MAVS and MAV-Nots: PINK1 Clears Prion-like MAVS Aggregates to Extinguish Mitochondrial Inflammatory Signaling
por: Rai, Prashant, et al.
Publicado: (2021)

Intracellular bacteria engage a STING-TBK1-MVB12b pathway to enable paracrine cGAS-STING signaling
por: Nandakumar, Ramya, et al.
Publicado: (2019)

PPM1A silences cytosolic RNA sensing and antiviral defense through direct dephosphorylation of MAVS and TBK1
por: Xiang, Weiwen, et al.
Publicado: (2016)

Zyxin stabilizes RIG-I and MAVS interactions and promotes type I interferon response
por: Kouwaki, Takahisa, et al.
Publicado: (2017)

Cullin-5 Adaptor SPSB1 Controls NF-κB Activation Downstream of Multiple Signaling Pathways
por: Georgana, Iliana, et al.
Publicado: (2020)

Poxvirus Interactions with the Host Ubiquitin System
por: Lant, Sian, et al.
Publicado: (2021)

The Cytosolic DNA-Sensing cGAS-STING Pathway in Liver Diseases
por: Wang, Zhilei, et al.
Publicado: (2021)

Vaccinia virus protein A49 activates Wnt signalling by targetting the E3 ligase β-TrCP
por: Maluquer de Motes, Carlos, et al.
Publicado: (2017)

MAVS polymers smaller than 80 nm induce mitochondrial membrane remodeling and interferon signaling
por: Hwang, Ming‐Shih, et al.
Publicado: (2019)

Dampened STING-Dependent Interferon Activation in Bats
por: Xie, Jiazheng, et al.
Publicado: (2018)

The opportunistic intracellular bacterial pathogen Rhodococcus equi elicits type I interferon by engaging cytosolic DNA sensing in macrophages
por: Vail, Krystal J., et al.
Publicado: (2021)

Mitochondrial damage and activation of the cytosolic DNA sensor cGAS–STING pathway lead to cardiac pyroptosis and hypertrophy in diabetic cardiomyopathy mice
por: Yan, Meiling, et al.
Publicado: (2022)

Identification of Cytosolic DNA Sensor cGAS-STING as Immune-Related Risk Factor in Renal Carcinoma following Pan-Cancer Analysis
por: Wu, Zheng, et al.
Publicado: (2022)

Foreign RNA Induces the Degradation of Mitochondrial Antiviral Signaling Protein (MAVS): The Role of Intracellular Antiviral Factors
por: Xing, Fei, et al.
Publicado: (2012)

Aggregation of MAVS antiviral protein suggests a mechanism for increased type I interferon production in SLE
por: Shao, Wen-Hai, et al.
Publicado: (2014)

Activation of Type I and III Interferon Response by Mitochondrial and Peroxisomal MAVS and Inhibition by Hepatitis C Virus
por: Bender, Silke, et al.
Publicado: (2015)

MST4 negatively regulates type I interferons production via targeting MAVS-mediated pathway
por: Liu, Wei, et al.
Publicado: (2022)

Estado de resultados MAV /
por: Martínez-Vera, Rubén
Publicado: (1986)

Cytosolic DNA sensing through cGAS and STING is inactivated by gene mutations in pangolins
por: Fischer, Heinz, et al.
Publicado: (2020)

CX-5461 Treatment Leads to Cytosolic DNA-Mediated STING Activation in Ovarian Cancer
por: Cornelison, Robert, et al.
Publicado: (2021)

Polymersome-mediated cytosolic delivery of cyclic dinucleotide STING agonist enhances tumor immunotherapy
por: Zheng, Huan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_c44lhq1nmudcvbfa11qv8jc6m9