A Cytokine Circus with a Viral Ringleader: SARS-CoV-2-Associated Cytokine Storm Syndromes

An unbridled host immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is likely to underlie severe cases of the disease and has been labeled a ‘cytokine storm syndrome’ (CSS). Here, we emphasize that categorization of syndromes triggered by a completely novel pa...

Descripción completa

Detalles Bibliográficos
Autores principales: Cabler, Stephanie S., French, Anthony R., Orvedahl, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Opinion
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524648/
https://www.ncbi.nlm.nih.gov/pubmed/33051104
http://dx.doi.org/10.1016/j.molmed.2020.09.012
Descripción
Sumario:An unbridled host immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is likely to underlie severe cases of the disease and has been labeled a ‘cytokine storm syndrome’ (CSS). Here, we emphasize that categorization of syndromes triggered by a completely novel pathogen based on other seemingly similar, but potentially distinct, known entities is an inherently risky endeavor.

Ejemplares similares