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Mathematical analysis of the effects of controls on transmission dynamics of SARS-CoV-2

COVID-19, an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), starting from Wuhan city of China, plagued the world in the later part of 2019. We developed a deterministic model to study the transmission dynamics of the disease with two categories of the Susc...

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Detalles Bibliográficos
Autores principales: K. Asamoah, Joshua Kiddy, Bornaa, C.S., Seidu, Baba, Jin, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. on behalf of Faculty of Engineering, Alexandria University. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524680/
http://dx.doi.org/10.1016/j.aej.2020.09.033
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author K. Asamoah, Joshua Kiddy
Bornaa, C.S.
Seidu, Baba
Jin, Zhen
author_facet K. Asamoah, Joshua Kiddy
Bornaa, C.S.
Seidu, Baba
Jin, Zhen
author_sort K. Asamoah, Joshua Kiddy
collection PubMed
description COVID-19, an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), starting from Wuhan city of China, plagued the world in the later part of 2019. We developed a deterministic model to study the transmission dynamics of the disease with two categories of the Susceptibles (ie Immigrant Susceptibles and Local Susceptible). The model is shown to have a globally stable disease-free equilibrium point whenever the basic reproduction number [Formula: see text] is less than unity. The endemic equilibrium is also shown to be globally stable for [Formula: see text] under some conditions. The spread of the disease is also shown to be highly sensitive to use of PPEs and personal hygiene [Formula: see text] , transmission probability [Formula: see text] , average number of contacts of infected person per unit time (day) [Formula: see text] , the rate at which the exposed develop clinical symptoms [Formula: see text] and the rate of recovery [Formula: see text]. Numerical simulation of the model is also done to illustrate the analytical results established.
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spelling pubmed-75246802020-09-30 Mathematical analysis of the effects of controls on transmission dynamics of SARS-CoV-2 K. Asamoah, Joshua Kiddy Bornaa, C.S. Seidu, Baba Jin, Zhen Alexandria Engineering Journal Article COVID-19, an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), starting from Wuhan city of China, plagued the world in the later part of 2019. We developed a deterministic model to study the transmission dynamics of the disease with two categories of the Susceptibles (ie Immigrant Susceptibles and Local Susceptible). The model is shown to have a globally stable disease-free equilibrium point whenever the basic reproduction number [Formula: see text] is less than unity. The endemic equilibrium is also shown to be globally stable for [Formula: see text] under some conditions. The spread of the disease is also shown to be highly sensitive to use of PPEs and personal hygiene [Formula: see text] , transmission probability [Formula: see text] , average number of contacts of infected person per unit time (day) [Formula: see text] , the rate at which the exposed develop clinical symptoms [Formula: see text] and the rate of recovery [Formula: see text]. Numerical simulation of the model is also done to illustrate the analytical results established. The Authors. Published by Elsevier B.V. on behalf of Faculty of Engineering, Alexandria University. 2020-12 2020-09-30 /pmc/articles/PMC7524680/ http://dx.doi.org/10.1016/j.aej.2020.09.033 Text en © 2020 The Authors. Published by Elsevier B.V. on behalf of Faculty of Engineering, Alexandria University. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
K. Asamoah, Joshua Kiddy
Bornaa, C.S.
Seidu, Baba
Jin, Zhen
Mathematical analysis of the effects of controls on transmission dynamics of SARS-CoV-2
title Mathematical analysis of the effects of controls on transmission dynamics of SARS-CoV-2
title_full Mathematical analysis of the effects of controls on transmission dynamics of SARS-CoV-2
title_fullStr Mathematical analysis of the effects of controls on transmission dynamics of SARS-CoV-2
title_full_unstemmed Mathematical analysis of the effects of controls on transmission dynamics of SARS-CoV-2
title_short Mathematical analysis of the effects of controls on transmission dynamics of SARS-CoV-2
title_sort mathematical analysis of the effects of controls on transmission dynamics of sars-cov-2
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524680/
http://dx.doi.org/10.1016/j.aej.2020.09.033
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