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Mathematical analysis of the effects of controls on transmission dynamics of SARS-CoV-2
COVID-19, an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), starting from Wuhan city of China, plagued the world in the later part of 2019. We developed a deterministic model to study the transmission dynamics of the disease with two categories of the Susc...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Authors. Published by Elsevier B.V. on behalf of Faculty of Engineering, Alexandria University.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524680/ http://dx.doi.org/10.1016/j.aej.2020.09.033 |
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author | K. Asamoah, Joshua Kiddy Bornaa, C.S. Seidu, Baba Jin, Zhen |
author_facet | K. Asamoah, Joshua Kiddy Bornaa, C.S. Seidu, Baba Jin, Zhen |
author_sort | K. Asamoah, Joshua Kiddy |
collection | PubMed |
description | COVID-19, an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), starting from Wuhan city of China, plagued the world in the later part of 2019. We developed a deterministic model to study the transmission dynamics of the disease with two categories of the Susceptibles (ie Immigrant Susceptibles and Local Susceptible). The model is shown to have a globally stable disease-free equilibrium point whenever the basic reproduction number [Formula: see text] is less than unity. The endemic equilibrium is also shown to be globally stable for [Formula: see text] under some conditions. The spread of the disease is also shown to be highly sensitive to use of PPEs and personal hygiene [Formula: see text] , transmission probability [Formula: see text] , average number of contacts of infected person per unit time (day) [Formula: see text] , the rate at which the exposed develop clinical symptoms [Formula: see text] and the rate of recovery [Formula: see text]. Numerical simulation of the model is also done to illustrate the analytical results established. |
format | Online Article Text |
id | pubmed-7524680 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | The Authors. Published by Elsevier B.V. on behalf of Faculty of Engineering, Alexandria University. |
record_format | MEDLINE/PubMed |
spelling | pubmed-75246802020-09-30 Mathematical analysis of the effects of controls on transmission dynamics of SARS-CoV-2 K. Asamoah, Joshua Kiddy Bornaa, C.S. Seidu, Baba Jin, Zhen Alexandria Engineering Journal Article COVID-19, an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), starting from Wuhan city of China, plagued the world in the later part of 2019. We developed a deterministic model to study the transmission dynamics of the disease with two categories of the Susceptibles (ie Immigrant Susceptibles and Local Susceptible). The model is shown to have a globally stable disease-free equilibrium point whenever the basic reproduction number [Formula: see text] is less than unity. The endemic equilibrium is also shown to be globally stable for [Formula: see text] under some conditions. The spread of the disease is also shown to be highly sensitive to use of PPEs and personal hygiene [Formula: see text] , transmission probability [Formula: see text] , average number of contacts of infected person per unit time (day) [Formula: see text] , the rate at which the exposed develop clinical symptoms [Formula: see text] and the rate of recovery [Formula: see text]. Numerical simulation of the model is also done to illustrate the analytical results established. The Authors. Published by Elsevier B.V. on behalf of Faculty of Engineering, Alexandria University. 2020-12 2020-09-30 /pmc/articles/PMC7524680/ http://dx.doi.org/10.1016/j.aej.2020.09.033 Text en © 2020 The Authors. Published by Elsevier B.V. on behalf of Faculty of Engineering, Alexandria University. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article K. Asamoah, Joshua Kiddy Bornaa, C.S. Seidu, Baba Jin, Zhen Mathematical analysis of the effects of controls on transmission dynamics of SARS-CoV-2 |
title | Mathematical analysis of the effects of controls on transmission dynamics of SARS-CoV-2 |
title_full | Mathematical analysis of the effects of controls on transmission dynamics of SARS-CoV-2 |
title_fullStr | Mathematical analysis of the effects of controls on transmission dynamics of SARS-CoV-2 |
title_full_unstemmed | Mathematical analysis of the effects of controls on transmission dynamics of SARS-CoV-2 |
title_short | Mathematical analysis of the effects of controls on transmission dynamics of SARS-CoV-2 |
title_sort | mathematical analysis of the effects of controls on transmission dynamics of sars-cov-2 |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524680/ http://dx.doi.org/10.1016/j.aej.2020.09.033 |
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