Cargando…
Pilot study on the therapeutic potential of radiofrequency magnetic fields: growth inhibition of implanted tumours in mice
The present study investigated possible therapeutic effects of radiofrequency or hypomagnetic fields on the growth rate of two types of implanted tumours. To this end, mice with implanted fibrosarcoma and pancreatic tumours were exposed continuously to a 2 µT, 10 MHz radiofrequency magnetic field (M...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524722/ https://www.ncbi.nlm.nih.gov/pubmed/32684625 http://dx.doi.org/10.1038/s41416-020-0995-3 |
_version_ | 1783588600745558016 |
---|---|
author | Luukkonen, Jukka Naarala, Jonne Juutilainen, Jukka Barnes, Frank Martino, Carlos F. |
author_facet | Luukkonen, Jukka Naarala, Jonne Juutilainen, Jukka Barnes, Frank Martino, Carlos F. |
author_sort | Luukkonen, Jukka |
collection | PubMed |
description | The present study investigated possible therapeutic effects of radiofrequency or hypomagnetic fields on the growth rate of two types of implanted tumours. To this end, mice with implanted fibrosarcoma and pancreatic tumours were exposed continuously to a 2 µT, 10 MHz radiofrequency magnetic field (MF) perpendicular to a 45 µT static MF or to a hypomagnetic (~0.4–1 µT) field. The reasoning for a 10 MHz treatment was based on a current theoretical explanation for MF effects, which predicts a resonance phenomenon in this frequency range. Radiofrequency MFs reduced consistently the growth rate of two implanted tumour types (by ~30% in both cases). Also, hypomagnetic field hindered tumour growth in both tumour types, but the observation was not statistically significant with fibrosarcoma tumours. In conclusion, although experiments included a limited number of animals, the results indicate that MFs may offer a novel therapeutic strategy in the treatment of cancer. |
format | Online Article Text |
id | pubmed-7524722 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-75247222021-07-20 Pilot study on the therapeutic potential of radiofrequency magnetic fields: growth inhibition of implanted tumours in mice Luukkonen, Jukka Naarala, Jonne Juutilainen, Jukka Barnes, Frank Martino, Carlos F. Br J Cancer Brief Communication The present study investigated possible therapeutic effects of radiofrequency or hypomagnetic fields on the growth rate of two types of implanted tumours. To this end, mice with implanted fibrosarcoma and pancreatic tumours were exposed continuously to a 2 µT, 10 MHz radiofrequency magnetic field (MF) perpendicular to a 45 µT static MF or to a hypomagnetic (~0.4–1 µT) field. The reasoning for a 10 MHz treatment was based on a current theoretical explanation for MF effects, which predicts a resonance phenomenon in this frequency range. Radiofrequency MFs reduced consistently the growth rate of two implanted tumour types (by ~30% in both cases). Also, hypomagnetic field hindered tumour growth in both tumour types, but the observation was not statistically significant with fibrosarcoma tumours. In conclusion, although experiments included a limited number of animals, the results indicate that MFs may offer a novel therapeutic strategy in the treatment of cancer. Nature Publishing Group UK 2020-07-20 2020-09-29 /pmc/articles/PMC7524722/ /pubmed/32684625 http://dx.doi.org/10.1038/s41416-020-0995-3 Text en © Cancer Research UK 2020 https://creativecommons.org/licenses/by/4.0/Note This work is published under the standard license to publish agreement. After 12 months the work will become freely available and the license terms will switch to a Creative Commons Attribution 4.0 International (CC BY 4.0). |
spellingShingle | Brief Communication Luukkonen, Jukka Naarala, Jonne Juutilainen, Jukka Barnes, Frank Martino, Carlos F. Pilot study on the therapeutic potential of radiofrequency magnetic fields: growth inhibition of implanted tumours in mice |
title | Pilot study on the therapeutic potential of radiofrequency magnetic fields: growth inhibition of implanted tumours in mice |
title_full | Pilot study on the therapeutic potential of radiofrequency magnetic fields: growth inhibition of implanted tumours in mice |
title_fullStr | Pilot study on the therapeutic potential of radiofrequency magnetic fields: growth inhibition of implanted tumours in mice |
title_full_unstemmed | Pilot study on the therapeutic potential of radiofrequency magnetic fields: growth inhibition of implanted tumours in mice |
title_short | Pilot study on the therapeutic potential of radiofrequency magnetic fields: growth inhibition of implanted tumours in mice |
title_sort | pilot study on the therapeutic potential of radiofrequency magnetic fields: growth inhibition of implanted tumours in mice |
topic | Brief Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524722/ https://www.ncbi.nlm.nih.gov/pubmed/32684625 http://dx.doi.org/10.1038/s41416-020-0995-3 |
work_keys_str_mv | AT luukkonenjukka pilotstudyonthetherapeuticpotentialofradiofrequencymagneticfieldsgrowthinhibitionofimplantedtumoursinmice AT naaralajonne pilotstudyonthetherapeuticpotentialofradiofrequencymagneticfieldsgrowthinhibitionofimplantedtumoursinmice AT juutilainenjukka pilotstudyonthetherapeuticpotentialofradiofrequencymagneticfieldsgrowthinhibitionofimplantedtumoursinmice AT barnesfrank pilotstudyonthetherapeuticpotentialofradiofrequencymagneticfieldsgrowthinhibitionofimplantedtumoursinmice AT martinocarlosf pilotstudyonthetherapeuticpotentialofradiofrequencymagneticfieldsgrowthinhibitionofimplantedtumoursinmice |