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A defined N6-methyladenosine (m(6)A) profile conferred by METTL3 regulates muscle stem cell/myoblast state transitions
Muscle-specific adult stem cells (MuSCs) are required for skeletal muscle regeneration. To ensure efficient skeletal muscle regeneration after injury, MuSCs must undergo state transitions as they are activated from quiescence, give rise to a population of proliferating myoblasts, and continue either...
Autores principales: | Gheller, Brandon J., Blum, Jamie E., Fong, Ern Hwei Hannah, Malysheva, Olga V., Cosgrove, Benjamin D., Thalacker-Mercer, Anna E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524727/ https://www.ncbi.nlm.nih.gov/pubmed/33083017 http://dx.doi.org/10.1038/s41420-020-00328-5 |
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