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Omidenepag, a non-prostanoid EP2 receptor agonist, induces enlargement of the 3D organoid of 3T3-L1 cells

2D and 3D cultures of 3T3-L1 cells were employed in a study of the effects of Omidenepag (OMD), interacting with a non-prostanoid EP2 receptor, on adipogenesis. Upon adipogenesis, the effects on lipid staining, the mRNA expression of adipogenesis-related genes (Pparγ, CEBPa, Ap2, and Glut4) and the...

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Detalles Bibliográficos
Autores principales: Ida, Yosuke, Hikage, Fumihito, Umetsu, Araya, Ida, Haruka, Ohguro, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524797/
https://www.ncbi.nlm.nih.gov/pubmed/32994409
http://dx.doi.org/10.1038/s41598-020-72538-x