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TSPO PET detects acute neuroinflammation but not diffuse chronically activated MHCII microglia in the rat

BACKGROUND: Accurate and sensitive imaging biomarkers are required to study the progression of white matter (WM) inflammation in neurodegenerative diseases. Radioligands targeting the translocator protein (TSPO) are considered sensitive indicators of neuroinflammation, but it is not clear how well t...

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Detalles Bibliográficos
Autores principales:	Al-Khishman, Nassir U., Qi, Qi, Roseborough, Austyn D., Levit, Alexander, Allman, Brian L., Anazodo, Udunna C., Fox, Matthew S., Whitehead, Shawn N., Thiessen, Jonathan D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524910/ https://www.ncbi.nlm.nih.gov/pubmed/32990808 http://dx.doi.org/10.1186/s13550-020-00699-x

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