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Inhibitory Effect of Imperatorin on the Pharmacokinetics of Diazepam In Vitro and In Vivo
BACKGROUND: Diazepam is a benzodiazepine drug used to treat anxiety, insomnia, and muscle spasms. Imperatorin is a phytochemical isolated from medicinal plants and is widely used in herbal medicine. The aim of this study was to investigate the interactions between imperatorin and diazepam in vitro a...
Autores principales: | Zhou, Yunfang, Meng, Deru, Chen, Feifei, Wu, Zhengping, Wang, Binglan, Wang, Shuanghu, Geng, Peiwu, Dai, Dapeng, Zhou, Quan, Qiu, Weiwen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525091/ https://www.ncbi.nlm.nih.gov/pubmed/33041783 http://dx.doi.org/10.3389/fphar.2020.01079 |
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