Cargando…

Sanqi Oral Solution Ameliorates Renal Ischemia/Reperfusion Injury via Reducing Apoptosis and Enhancing Autophagy: Involvement of ERK/mTOR Pathways

Ischemia-reperfusion (I/R) induced acute kidney injury (AKI) is a significant health problem with high morbidity and mortality, yet prophylaxis strategies and effective drugs are limited. Sanqi oral solution (SQ) is a formulated medicine widely used in clinical settings to treat various renal diseas...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tian, Ruimin, Wang, Pinchao, Huang, Lihua, Li, Chuang, Lu, Zhaoyu, Lu, Zhisheng, Wu, Aijun, Bao, Kun, Mao, Wei, Huang, Qingming, Xu, Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525120/ https://www.ncbi.nlm.nih.gov/pubmed/33041791 http://dx.doi.org/10.3389/fphar.2020.537147

Ejemplares similares

Sanqi Oral Solution Mitigates Proteinuria in Rat Passive Heymann Nephritis and Blocks Podocyte Apoptosis via Nrf2/HO-1 Pathway
por: Wang, Xiaowan, et al.
Publicado: (2021)

Corrigendum: Sanqi Oral Solution Mitigates Proteinuria in Rat Passive Heymann Nephritis and Blocks Podocyte Apoptosis via Nrf2/HO-1 Pathway
por: Wang, Xiaowan, et al.
Publicado: (2022)

Exogenous NADPH ameliorates myocardial ischemia–reperfusion injury in rats through activating AMPK/mTOR pathway
por: Zhu, Jiang, et al.
Publicado: (2019)

Protective Role of mTOR in Liver Ischemia/Reperfusion Injury: Involvement of Inflammation and Autophagy
por: Zhang, Tao, et al.
Publicado: (2019)

Snapshot: Implications for mTOR in Aging-related Ischemia/Reperfusion Injury
por: Liu, Dong, et al.
Publicado: (2019)

Metabonomic Analysis of the Therapeutic Effects of Chinese Medicine Sanqi Oral Solution on Rats With Exhaustive Exercise
por: Xu, Peng, et al.
Publicado: (2019)

The role of mTOR signaling pathway on cognitive functions in cerebral ischemia-reperfusion
por: Yang, Liying, et al.
Publicado: (2017)

Ibrutinib ameliorates cerebral ischemia/reperfusion injury through autophagy activation and PI3K/Akt/mTOR signaling pathway in diabetic mice
por: Jin, Lei, et al.
Publicado: (2021)

Interaction of mTOR and iNOS pathways in protection against Ischemia/Reperfusion injury
por: Arabian, Maedeh, et al.
Publicado: (2019)

Sanqi Panax Notoginseng Injection for Angina Pectoris
por: Yang, Xiaochen, et al.
Publicado: (2014)

ProNGF/NGF Modulates Autophagy and Apoptosis through PI3K/Akt/mTOR and ERK Signaling Pathways following Cerebral Ischemia-Reperfusion in Rats
por: Li, Yanbo, et al.
Publicado: (2022)

Roles of Akt and ERK in mTOR-Dependent Antidepressant Effects of Vanillic Acid
por: Chuang, Han-Wen, et al.
Publicado: (2020)

Lithium chloride ameliorated spatial cognitive impairment through activating mTOR phosphorylation and inhibiting excessive autophagy in the repeated cerebral ischemia-reperfusion mouse model
por: Xiao, Yining, et al.
Publicado: (2020)

mTOR/autophagy pathway in the hippocampus of rats suffering intermittent hypoxia preconditioning and global cerebral ischemia-reperfusion
por: Zhao, Ya-Ning, et al.
Publicado: (2017)

Eugenol Attenuates Cerebral Ischemia-Reperfusion Injury by Enhancing Autophagy via AMPK-mTOR-P70S6K Pathway
por: Sun, Xiaowei, et al.
Publicado: (2020)

ERK/mTOR signaling may underlying the antidepressant actions of rapastinel in mice
por: Shen, Mengxin, et al.
Publicado: (2022)

Oleic Acid Protects against Hepatic Ischemia and Reperfusion Injury in Mice by Inhibiting AKT/mTOR Pathways
por: Guo, Jianrong, et al.
Publicado: (2019)

Insights for Oxidative Stress and mTOR Signaling in Myocardial Ischemia/Reperfusion Injury under Diabetes
por: Zhao, Dajun, et al.
Publicado: (2017)

Stereoisomers of Saponins in Panax notoginseng (Sanqi): A Review
por: Peng, Ming, et al.
Publicado: (2018)

Dexmedetomidine postconditioning suppresses myocardial ischemia/reperfusion injury by activating the SIRT1/mTOR axis
por: Zhang, Xiong, et al.
Publicado: (2020)

mTOR‐mediated calcium transients affect cardiac function in ex vivo ischemia–reperfusion injury
por: Shimada, Briana K., et al.
Publicado: (2021)

Effects of mTOR on Neurological Deficits after Transient Global Ischemia
por: Xing, Jihong, et al.
Publicado: (2017)

Effects of propofol on LC3II and mTOR/p-mTOR expression during ischemia-reperfusion myocardium injury in rats with type 2 diabetes mellitus
por: Wang, Ying, et al.
Publicado: (2020)

bFGF regulates autophagy and ubiquitinated protein accumulation induced by myocardial ischemia/reperfusion via the activation of the PI3K/Akt/mTOR pathway
por: Wang, Zhou-Guang, et al.
Publicado: (2015)

Electroacupuncture Ameliorates Cerebral Ischemia-Reperfusion Injury by Regulation of Autophagy and Apoptosis
por: Shu, Shi, et al.
Publicado: (2016)

Puerarin protects rat brain against ischemia/reperfusion injury by suppressing autophagy via the AMPK-mTOR-ULK1 signaling pathway
por: Wang, Jin-Feng, et al.
Publicado: (2018)

MicroRNA-101 inhibits autophagy to alleviate liver ischemia/reperfusion injury via regulating the mTOR signaling pathway
por: Song, Hu, et al.
Publicado: (2019)

MicroRNA-101 inhibits autophagy to alleviate liver ischemia/reperfusion injury via regulating the mTOR signaling pathway
por: Song, Hu, et al.
Publicado: (2019)

Suxiao Jiuxin Pill alleviates myocardial ischemia–reperfusion injury through the ALKBH5/GSK3β/mTOR pathway
por: Li, Yiping, et al.
Publicado: (2023)

Network pharmacology-based strategy for predicting therapy targets of Sanqi and Huangjing in diabetes mellitus
por: Cui, Xiao-Yan, et al.
Publicado: (2022)

Dihydromyricetin Attenuates Cerebral Ischemia Reperfusion Injury by Inhibiting SPHK1/mTOR Signaling and Targeting Ferroptosis
por: Xie, Jiangbo, et al.
Publicado: (2022)

Retraction: Dexmedetomidine postconditioning suppresses myocardial ischemia/reperfusion injury by activating the SIRT1/mTOR axis
Publicado: (2022)

Myocardial Ischemic Postconditioning Promotes Autophagy against Ischemia Reperfusion Injury via the Activation of the nNOS/AMPK/mTOR Pathway
por: Hao, Maojuan, et al.
Publicado: (2017)

Cornin protects against cerebral ischemia/reperfusion injury by preventing autophagy via the PI3K/Akt/mTOR pathway
por: Lan, Tianchi, et al.
Publicado: (2022)

Coxsackievirus A16 Elicits Incomplete Autophagy Involving the mTOR and ERK Pathways
por: Shi, Yingying, et al.
Publicado: (2015)

Dysregulation of mTOR Signaling after Brain Ischemia
por: Villa-González, Mario, et al.
Publicado: (2022)

Echinacoside exhibits antidepressant-like effects through AMPAR–Akt/ERK–mTOR pathway stimulation and BDNF expression in mice
por: Chuang, Han-Wen, et al.
Publicado: (2022)

Orf virus induces complete autophagy to promote viral replication via inhibition of AKT/mTOR and activation of the ERK1/2/mTOR signalling pathway in OFTu cells
por: Lv, Lijun, et al.
Publicado: (2023)

Aescin Protects Neuron from Ischemia-Reperfusion Injury via Regulating the PRAS40/mTOR Signaling Pathway
por: Gao, Xinjie, et al.
Publicado: (2020)

PPARγ Plays an Important Role in Acute Hepatic Ischemia-Reperfusion Injury via AMPK/mTOR Pathway
por: Wu, Liwei, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_mfgr2rjvonhleha0cgbb5bgah2