Establishment of Quantitative PCR Assays for Active Long Interspersed Nuclear Element-1 Subfamilies in Mice and Applications to the Analysis of Aging-Associated Retrotransposition

The retrotransposon long interspersed nuclear element-1 (LINE-1) can autonomously increase its copy number within a host genome through the retrotransposition process. LINE-1 is active in the germline and in neural progenitor cells, and its somatic retrotransposition activity has a broad impact on n...

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Detalles Bibliográficos
Autores principales: Kuroki, Ryota, Murata, Yui, Fuke, Satoshi, Nakachi, Yutaka, Nakashima, Jun, Kujoth, Gregory C., Prolla, Tomas A., Bundo, Miki, Kato, Tadafumi, Iwamoto, Kazuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525186/
https://www.ncbi.nlm.nih.gov/pubmed/33193604
http://dx.doi.org/10.3389/fgene.2020.519206

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