IL-6 serum levels predict severity and response to tocilizumab in COVID-19: An observational study

BACKGROUND: Patients with coronavirus disaese 2019 (COVID-19) can develop a cytokine release syndrome that eventually leads to acute respiratory distress syndrome requiring invasive mechanical ventilation (IMV). Because IL-6 is a relevant cytokine in acute respiratory distress syndrome, the blockade...

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Detalles Bibliográficos
Autores principales: Galván-Román, José María, Rodríguez-García, Sebastián C., Roy-Vallejo, Emilia, Marcos-Jiménez, Ana, Sánchez-Alonso, Santiago, Fernández-Díaz, Carlos, Alcaraz-Serna, Ana, Mateu-Albero, Tamara, Rodríguez-Cortes, Pablo, Sánchez-Cerrillo, Ildefonso, Esparcia, Laura, Martínez-Fleta, Pedro, López-Sanz, Celia, Gabrie, Ligia, del Campo Guerola, Luciana, Suárez-Fernández, Carmen, Ancochea, Julio, Canabal, Alfonso, Albert, Patricia, Rodríguez-Serrano, Diego A., Aguilar, Juan Mariano, del Arco, Carmen, de los Santos, Ignacio, García-Fraile, Lucio, de la Cámara, Rafael, Serra, José María, Ramírez, Esther, Alonso, Tamara, Landete, Pedro, Soriano, Joan B., Martín-Gayo, Enrique, Fraile Torres, Arturo, Zurita Cruz, Nelly Daniela, García-Vicuña, Rosario, Cardeñoso, Laura, Sánchez-Madrid, Francisco, Alfranca, Arantzazu, Muñoz-Calleja, Cecilia, González-Álvaro, Isidoro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Academy of Allergy, Asthma & Immunology 2021
Materias:
Covid-19
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525244/
https://www.ncbi.nlm.nih.gov/pubmed/33010257
http://dx.doi.org/10.1016/j.jaci.2020.09.018

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