The acidic tumor microenvironment drives a stem-like phenotype in melanoma cells

ABSTRACT: Acidosis characterizes the microenvironment of most solid tumors and is considered a new hallmark of cancer. It is mainly caused by both “aerobic” and “anaerobic” glycolysis of differently adapted cancer cells, with the final product lactic acid being responsible of the extracellular acidi...

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Detalles Bibliográficos
Autores principales: Andreucci, Elena, Peppicelli, Silvia, Ruzzolini, Jessica, Bianchini, Francesca, Biagioni, Alessio, Papucci, Laura, Magnelli, Lucia, Mazzanti, Benedetta, Stecca, Barbara, Calorini, Lido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525286/
https://www.ncbi.nlm.nih.gov/pubmed/32803272
http://dx.doi.org/10.1007/s00109-020-01959-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525286/
https://www.ncbi.nlm.nih.gov/pubmed/32803272
http://dx.doi.org/10.1007/s00109-020-01959-y

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