Amyloid Beta-Peptide Increases BACE1 Translation through the Phosphorylation of the Eukaryotic Initiation Factor-2α

Alzheimer's disease (AD) is tightly linked to oxidative stress since amyloid beta-peptide (Aβ) aggregates generate free radicals. Moreover, the aggregation of Aβ is increased by oxidative stress, and the neurotoxicity induced by the oligomers and fibrils is in part mediated by free radicals. In...

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Detalles Bibliográficos
Autores principales: Picón-Pagès, Pol, Gutiérrez, Daniela A., Barranco-Almohalla, Alejandro, Crepin, Giulia, Tajes, Marta, ILL-Raga, Gerard, Guix, Francesc X., Menéndez, Silvia, Arumí-Uría, Montserrat, Vicente, Rubén, Álvarez, Alejandra R., Muñoz, Francisco J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525306/
https://www.ncbi.nlm.nih.gov/pubmed/33014268
http://dx.doi.org/10.1155/2020/2739459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525306/
https://www.ncbi.nlm.nih.gov/pubmed/33014268
http://dx.doi.org/10.1155/2020/2739459

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