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Variations in MHC class I antigen presentation and immunopeptidome selection pathways

Major histocompatibility class I (MHC-I) proteins mediate immunosurveillance against pathogens and cancers by presenting antigenic or mutated peptides to antigen receptors of CD8+ T cells and by engaging receptors of natural killer (NK) cells. In humans, MHC-I molecules are highly polymorphic. MHC-I...

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Detalles Bibliográficos
Autores principales:	Zaitouna, Anita J., Kaur, Amanpreet, Raghavan, Malini
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	F1000 Research Limited 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525337/ https://www.ncbi.nlm.nih.gov/pubmed/33014341 http://dx.doi.org/10.12688/f1000research.26935.1

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