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Mitochondrial Calcium Uniporter (MCU) deficiency reveals an alternate path for Ca(2+) uptake in photoreceptor mitochondria
Rods and cones use intracellular Ca(2+) to regulate many functions, including phototransduction and neurotransmission. The Mitochondrial Calcium Uniporter (MCU) complex is thought to be the primary pathway for Ca(2+) entry into mitochondria in eukaryotes. We investigate the hypothesis that mitochond...
Autores principales: | Bisbach, Celia M., Hutto, Rachel A., Poria, Deepak, Cleghorn, Whitney M., Abbas, Fatima, Vinberg, Frans, Kefalov, Vladimir J., Hurley, James B., Brockerhoff, Susan E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525533/ https://www.ncbi.nlm.nih.gov/pubmed/32994451 http://dx.doi.org/10.1038/s41598-020-72708-x |
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