bFGF blockade reduces intraplaque angiogenesis and macrophage infiltration in atherosclerotic vein graft lesions in ApoE3*Leiden mice

Intraplaque angiogenesis increases the chance of unstable atherosclerotic plaque rupture and thrombus formation leading to myocardial infarction. Basic Fibroblast Growth Factor (bFGF) plays a key role in angiogenesis and inflammation and is involved in the pathogenesis of atherosclerosis. Therefore,...

Descripción completa

Detalles Bibliográficos
Autores principales: Parma, Laura, Peters, Hendrika A. B., Sluiter, Thijs J., Simons, Karin H., Lazzari, Paolo, de Vries, Margreet R., Quax, Paul H. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525538/
https://www.ncbi.nlm.nih.gov/pubmed/32994514
http://dx.doi.org/10.1038/s41598-020-72992-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525538/
https://www.ncbi.nlm.nih.gov/pubmed/32994514
http://dx.doi.org/10.1038/s41598-020-72992-7

Ejemplares similares