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bFGF blockade reduces intraplaque angiogenesis and macrophage infiltration in atherosclerotic vein graft lesions in ApoE3*Leiden mice

Intraplaque angiogenesis increases the chance of unstable atherosclerotic plaque rupture and thrombus formation leading to myocardial infarction. Basic Fibroblast Growth Factor (bFGF) plays a key role in angiogenesis and inflammation and is involved in the pathogenesis of atherosclerosis. Therefore,...

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Detalles Bibliográficos
Autores principales:	Parma, Laura, Peters, Hendrika A. B., Sluiter, Thijs J., Simons, Karin H., Lazzari, Paolo, de Vries, Margreet R., Quax, Paul H. A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525538/ https://www.ncbi.nlm.nih.gov/pubmed/32994514 http://dx.doi.org/10.1038/s41598-020-72992-7

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