Cargando…

Tumor necrosis factor-α requires Ezrin to regulate the cytoskeleton and cause pulmonary microvascular endothelial barrier damage

Acute respiratory distress syndrome (ARDS) is a rapidly progressive disease with unknown pathogenesis. Damage of pulmonary microvascular endothelial cells (PMVECs) caused by inflammatory storm caused by cytokines such as TNF-α is the potential pathogenesis of ARDS. In this study, we examined the rol...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tang, Sihui, Jiang, Jianjun, Zhang, Na, Sun, Juan, Sun, Gengyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525657/ https://www.ncbi.nlm.nih.gov/pubmed/33007316 http://dx.doi.org/10.1016/j.mvr.2020.104093

Ejemplares similares

Inflammatory Immune Cytokine TNF-α Modulates Ezrin Protein Activation via FAK/RhoA Signaling Pathway in PMVECs Hyperpermeability
por: Zhou, Qun, et al.
Publicado: (2021)

Ezrin Regulating the Cytoskeleton Remodeling is Required for Hypoxia-Induced Myofibroblast Proliferation and Migration
por: Yi, Bin, et al.
Publicado: (2015)

Ezrin is essential for the entry of Japanese encephalitis virus into the human brain microvascular endothelial cells
por: Liu, Yan-Gang, et al.
Publicado: (2020)

Nuclear Import of β-Dystroglycan Is Facilitated by Ezrin-Mediated Cytoskeleton Reorganization
por: Vásquez-Limeta, Alejandra, et al.
Publicado: (2014)

miR‐642a‐5p partially mediates the effects of lipopolysaccharide on human pulmonary microvascular endothelial cells via eEF2
por: Fei, Liming, et al.
Publicado: (2020)

Acetylation of ezrin regulates membrane–cytoskeleton interaction underlying CCL18-elicited cell migration
por: Song, Xiaoyu, et al.
Publicado: (2019)

Ezrin is required for adhesion and migration in invasive breast cancer
por: Szeto, Alvin, et al.
Publicado: (2013)

The Changes of P-glycoprotein Activity by Interferon-γ and Tumor Necrosis Factor-α in Primary and Immortalized Human Brain Microvascular Endothelial Cells
por: Lee, Na-Young, et al.
Publicado: (2012)

Golgi Outposts Locally Regulate Microtubule Orientation in Neurons but Are Not Required for the Overall Polarity of the Dendritic Cytoskeleton
por: Yang, Sihui Z., et al.
Publicado: (2020)

Ezrin contains cytoskeleton and membrane binding domains accounting for its proposed role as a membrane-cytoskeletal linker
Publicado: (1993)

Expression of ezrin protein and phosphorylated ezrin in pelvic endometriotic lesions
por: Peloggia, Alessandra, et al.
Publicado: (2022)

CXCR6-CXCL16 axis promotes prostate cancer by mediating cytoskeleton rearrangement via Ezrin activation and α(v)β(3) integrin clustering
por: Singh, Rajesh, et al.
Publicado: (2016)

Steen solution protects pulmonary microvascular endothelial cells and preserves endothelial barrier after lipopolysaccharide-induced injury
por: Ta, Huy Q., et al.
Publicado: (2023)

Bioactive Ent-Kaurane Diterpenes Oridonin and Irudonin Prevent Cancer Cells Migration by Interacting with the Actin Cytoskeleton Controller Ezrin
por: Pagliara, Valentina, et al.
Publicado: (2020)

Schip1 Is a Novel Podocyte Foot Process Protein that Mediates Actin Cytoskeleton Rearrangements and Forms a Complex with Nherf2 and Ezrin
por: Perisic, Ljubica, et al.
Publicado: (2015)

Caveolin-1 Regulates Rac1 Activation and Rat Pulmonary Microvascular Endothelial Hyperpermeability Induced by TNF-α
por: Shao, Min, et al.
Publicado: (2013)

Barrier stabilizing mediators in regulation of microvascular endothelial permeability
por: Qiao-bing, Huang, et al.
Publicado: (2012)

The pulmonary microvascular endothelial barrier function is controlled by the PGE(2)-EP(4) signaling axis
por: Kónya, Viktória, et al.
Publicado: (2010)

The membrane cytoskeletal crosslinker ezrin is required for metastasis of breast carcinoma cells
por: Elliott, Bruce E, et al.
Publicado: (2005)

Ezrin and Moesin Are Required for Efficient T Cell Adhesion and Homing to Lymphoid Organs
por: Chen, Emily J. H., et al.
Publicado: (2013)

Transcriptional Analysis of Sepsis-Induced Activation and Damage of the Adrenal Endothelial Microvascular Cells
por: Chen, Lan-Sun, et al.
Publicado: (2020)

Correction: Schip1 Is a Novel Podocyte Foot Process Protein that Mediates Actin Cytoskeleton Rearrangements and Forms a Complex with Nherf2 and Ezrin
por: Perisic, Ljubica, et al.
Publicado: (2015)

Suilysin remodels the cytoskeletons of human brain microvascular endothelial cells by activating RhoA and Rac1 GTPase
por: Lv, Qingyu, et al.
Publicado: (2014)

Nitro Capsaicin Suppressed Microglial Activation and TNF-α-Induced Brain Microvascular Endothelial Cell Damage
por: Jamornwan, Sopana, et al.
Publicado: (2022)

Tumour necrosis factor α enhances CCL2 and ICAM-1 expression in peripheral nerve microvascular endoneurial endothelial cells
por: Langert, Kelly A., et al.
Publicado: (2013)

Differential Mechanisms of Septic Human Pulmonary Microvascular Endothelial Cell Barrier Dysfunction Depending on the Presence of Neutrophils
por: Wang, Lefeng, et al.
Publicado: (2018)

Imbalance of Pulmonary Microvascular Endothelial Cell-Expression of Metalloproteinases and Their Endogenous Inhibitors Promotes Septic Barrier Dysfunction †
por: Jayawardena, Devika P., et al.
Publicado: (2023)

Ezrin Is Required for the Functional Regulation of the Epithelial Sodium Proton Exchanger, NHE3
por: Hayashi, Hisayoshi, et al.
Publicado: (2013)

MRTF transcription and Ezrin-dependent plasma membrane blebbing are required for entotic invasion
por: Hinojosa, Laura Soto, et al.
Publicado: (2017)

Heat stress combined with lipopolysaccharide induces pulmonary microvascular endothelial cell glycocalyx inflammatory damage in vitro
por: Chen, Jiadi, et al.
Publicado: (2023)

Hemodynamics and the vascular endothelial cytoskeleton
Publicado: (1987)

Prognostic implications of ezrin and phosphorylated ezrin expression in non-small cell lung cancer
por: Jin, Tiefeng, et al.
Publicado: (2014)

Do viruses require the cytoskeleton?
por: Matthews, Jason D, et al.
Publicado: (2013)

Method for the Culture of Mouse Pulmonary Microvascular Endothelial Cells
por: Kovacs-Kàsa, Anita, et al.
Publicado: (2017)

Ezrin Immunoexpression in Prostate Adenocarcinomas
por: POPESCU, TUDOR CRISTIAN TIMOTEI, et al.
Publicado: (2022)

Dephosphorylation of Y685-VE-Cadherin Involved in Pulmonary Microvascular Endothelial Barrier Injury Induced by Angiotensin II
por: Wu, Zhiyong, et al.
Publicado: (2016)

Unfractionated heparin ameliorates pulmonary microvascular endothelial barrier dysfunction via microtubule stabilization in acute lung injury
por: Mu, Shengtian, et al.
Publicado: (2018)

Inhibition of Murine Pulmonary Microvascular Endothelial Cell Apoptosis Promotes Recovery of Barrier Function under Septic Conditions
por: Wang, Lefeng, et al.
Publicado: (2017)

Ezrin has a COOH-terminal actin-binding site that is conserved in the ezrin protein family
Publicado: (1994)

Autophagy regulates the therapeutic potential of adipose-derived stem cells in LPS-induced pulmonary microvascular barrier damage
por: Li, Chichi, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_0t2s3lngge1npu0hvtrftdjcqn