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Preclinical dosimetry models and the prediction of clinical doses of novel positron emission tomography radiotracers
Dosimetry models using preclinical positron emission tomography (PET) data are commonly employed to predict the clinical radiological safety of novel radiotracers. However, unbiased clinical safety profiling remains difficult during the translational exercise from preclinical research to first-in-hu...
Autores principales: | Garrow, Adam A., Andrews, Jack P. M., Gonzalez, Zaniah N., Corral, Carlos A., Portal, Christophe, Morgan, Timaeus E. F., Walton, Tashfeen, Wilson, Ian, Newby, David E., Lucatelli, Christophe, Tavares, Adriana A. S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525662/ https://www.ncbi.nlm.nih.gov/pubmed/32994530 http://dx.doi.org/10.1038/s41598-020-72830-w |
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