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IQGAP1 promotes anoikis resistance and metastasis through Rac1-dependent ROS accumulation and activation of Src/FAK signalling in hepatocellular carcinoma

BACKGROUND: Hepatitis B virus (HBV) has a crucial role in the progression of hepatocellular carcinoma (HCC). Tumour cells must develop anoikis resistance in order to survive before metastasis. This study aimed to investigate the mechanism of IQGAP1 in HBV-mediated anoikis evasion and metastasis in H...

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Detalles Bibliográficos
Autores principales:	Mo, Chun-fen, Li, Jun, Yang, Shu-xia, Guo, Hui-jie, Liu, Yang, Luo, Xing-yan, Wang, Yan-tang, Li, Min-hui, Li, Jing-yi, Zou, Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525663/ https://www.ncbi.nlm.nih.gov/pubmed/32632148 http://dx.doi.org/10.1038/s41416-020-0970-z

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