Roles for a lipid phosphatase in the activation of its opposing lipid kinase

Fig4 is a phosphoinositide phosphatase that converts PI3,5P2 to PI3P. Paradoxically, mutation of Fig4 results in lower PI3,5P2, indicating that Fig4 is also required for PI3,5P2 production. Fig4 promotes elevation of PI3,5P2, in part, through stabilization of a protein complex that includes its oppo...

Descripción completa

Detalles Bibliográficos
Autores principales: Strunk, Bethany S., Steinfeld, Noah, Lee, Sora, Jin, Natsuko, Muñoz-Rivera, Cecilia, Meeks, Garrison, Thomas, Asha, Akemann, Camille, Mapp, Anna K., MacGurn, Jason A., Weisman, Lois S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525815/
https://www.ncbi.nlm.nih.gov/pubmed/32583743
http://dx.doi.org/10.1091/mbc.E18-09-0556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525815/
https://www.ncbi.nlm.nih.gov/pubmed/32583743
http://dx.doi.org/10.1091/mbc.E18-09-0556

Ejemplares similares