Cargando…

Metabolic characterization of aggressive breast cancer cells exhibiting invasive phenotype: impact of non-cytotoxic doses of 2-DG on diminishing invasiveness

BACKGROUND: Metabolic reprogramming is being recognized as a fundamental hallmark of cancer, and efforts to identify drugs that can target cancer metabolism are underway. In this study, we used human breast cancer (BC) cell lines and established their invading phenotype (INV) collected from transwel...

Descripción completa

Detalles Bibliográficos
Autores principales: Fujita, Mayumi, Imadome, Kaori, Somasundaram, Veena, Kawanishi, Miki, Karasawa, Kumiko, Wink, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525976/
https://www.ncbi.nlm.nih.gov/pubmed/32993545
http://dx.doi.org/10.1186/s12885-020-07414-y