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Moderately high folate level may offset the effects of aberrant DNA methylation of P16 and P53 genes in esophageal squamous cell carcinoma and precancerous lesions

BACKGROUND: This study evaluated gene-nutrition interactions between folate and the aberrant DNA methylation of tumor suppressor genes in different stages of carcinogenesis of esophageal squamous cell carcinoma (ESCC). METHODS: Two hundred ESCC cases, 200 esophageal precancerous lesion (EPL) cases,...

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Detalles Bibliográficos
Autores principales:	Wang, Shaokang, Pan, Da, Su, Ming, Huang, Guiling, Sun, Guiju
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526188/ https://www.ncbi.nlm.nih.gov/pubmed/32993492 http://dx.doi.org/10.1186/s12263-020-00677-x

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