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Depressive disorders in Brazil: results from the Global Burden of Disease Study 2017

BACKGROUND: Depression is one of the major causes of disability worldwide. The objective of this study was to analyze the results of the Global Burden of Disease Study 2017 (GBD-2017) for depressive disorders in Brazil and its Federated Units (FUs) in 1990 and 2017. METHODS: We used GBD-2017 study m...

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Autores principales: Bonadiman, Cecília Silva Costa, Malta, Deborah Carvalho, de Azeredo Passos, Valéria Maria, Naghavi, Mohsen, Melo, Ana Paula Souto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526360/
https://www.ncbi.nlm.nih.gov/pubmed/32993670
http://dx.doi.org/10.1186/s12963-020-00204-5
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author Bonadiman, Cecília Silva Costa
Malta, Deborah Carvalho
de Azeredo Passos, Valéria Maria
Naghavi, Mohsen
Melo, Ana Paula Souto
author_facet Bonadiman, Cecília Silva Costa
Malta, Deborah Carvalho
de Azeredo Passos, Valéria Maria
Naghavi, Mohsen
Melo, Ana Paula Souto
author_sort Bonadiman, Cecília Silva Costa
collection PubMed
description BACKGROUND: Depression is one of the major causes of disability worldwide. The objective of this study was to analyze the results of the Global Burden of Disease Study 2017 (GBD-2017) for depressive disorders in Brazil and its Federated Units (FUs) in 1990 and 2017. METHODS: We used GBD-2017 study methodology to evaluate the prevalence estimates, the disability-adjusted life-year (DALY), and the years lived with disability (YLDs) for depressive disorders, which include major depressive disorder and dysthymia. The YLD estimates and the position of these disorders in the DALY and YLD rankings were compared to those of seven other countries. The observed versus expected YLD, based on the sociodemographic index (SDI), were compared. RESULTS: In GBD-2017, the prevalence of depressive disorders in Brazil was 3.30% (95% uncertainty interval [UI]: 3.08 to 3.57), ranging from 3.79% (3.53 to 4.09) in Santa Catarina to 2.78% in Pará (2.56 to 3.03), with significant differences between the Federated Units. From 1990 to 2017, there was an increase in number of YLD (55.19%, 49.57 to 60.73), but a decrease in the age-standardized rates (− 9.01%, − 11.66 to − 6.31). The highest proportion of YLD was observed in the age range of 15–64 years and among females. These disorders rank 4th and 13th as leading causes of YLD and DALY, respectively, in Brazil. In the other countries evaluated, the ranking of these disorders in the YLD classification was close to Brazil’s, while in the DALY classification, there was higher variability. All countries had YLD rates similar to the overall rate. The observed/expected YLD ratio ranged from 0.81 in Pará to 1.16 in Santa Catarina. Morbidity of depressive disorders was not associated with SDI. CONCLUSIONS: Depressive disorders have been responsible for a high disability burden since 1990, especially in adult women living in the Southern region of the country. The number of people affected by these disorders in the country tends to increase, requiring more investment in mental health aimed at advancements and quality of services. The epidemiological studies of these disorders throughout the national territory can contribute to this planning and to making the Brazilian health system more equitable.
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spelling pubmed-75263602020-10-01 Depressive disorders in Brazil: results from the Global Burden of Disease Study 2017 Bonadiman, Cecília Silva Costa Malta, Deborah Carvalho de Azeredo Passos, Valéria Maria Naghavi, Mohsen Melo, Ana Paula Souto Popul Health Metr Research BACKGROUND: Depression is one of the major causes of disability worldwide. The objective of this study was to analyze the results of the Global Burden of Disease Study 2017 (GBD-2017) for depressive disorders in Brazil and its Federated Units (FUs) in 1990 and 2017. METHODS: We used GBD-2017 study methodology to evaluate the prevalence estimates, the disability-adjusted life-year (DALY), and the years lived with disability (YLDs) for depressive disorders, which include major depressive disorder and dysthymia. The YLD estimates and the position of these disorders in the DALY and YLD rankings were compared to those of seven other countries. The observed versus expected YLD, based on the sociodemographic index (SDI), were compared. RESULTS: In GBD-2017, the prevalence of depressive disorders in Brazil was 3.30% (95% uncertainty interval [UI]: 3.08 to 3.57), ranging from 3.79% (3.53 to 4.09) in Santa Catarina to 2.78% in Pará (2.56 to 3.03), with significant differences between the Federated Units. From 1990 to 2017, there was an increase in number of YLD (55.19%, 49.57 to 60.73), but a decrease in the age-standardized rates (− 9.01%, − 11.66 to − 6.31). The highest proportion of YLD was observed in the age range of 15–64 years and among females. These disorders rank 4th and 13th as leading causes of YLD and DALY, respectively, in Brazil. In the other countries evaluated, the ranking of these disorders in the YLD classification was close to Brazil’s, while in the DALY classification, there was higher variability. All countries had YLD rates similar to the overall rate. The observed/expected YLD ratio ranged from 0.81 in Pará to 1.16 in Santa Catarina. Morbidity of depressive disorders was not associated with SDI. CONCLUSIONS: Depressive disorders have been responsible for a high disability burden since 1990, especially in adult women living in the Southern region of the country. The number of people affected by these disorders in the country tends to increase, requiring more investment in mental health aimed at advancements and quality of services. The epidemiological studies of these disorders throughout the national territory can contribute to this planning and to making the Brazilian health system more equitable. BioMed Central 2020-09-30 /pmc/articles/PMC7526360/ /pubmed/32993670 http://dx.doi.org/10.1186/s12963-020-00204-5 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Bonadiman, Cecília Silva Costa
Malta, Deborah Carvalho
de Azeredo Passos, Valéria Maria
Naghavi, Mohsen
Melo, Ana Paula Souto
Depressive disorders in Brazil: results from the Global Burden of Disease Study 2017
title Depressive disorders in Brazil: results from the Global Burden of Disease Study 2017
title_full Depressive disorders in Brazil: results from the Global Burden of Disease Study 2017
title_fullStr Depressive disorders in Brazil: results from the Global Burden of Disease Study 2017
title_full_unstemmed Depressive disorders in Brazil: results from the Global Burden of Disease Study 2017
title_short Depressive disorders in Brazil: results from the Global Burden of Disease Study 2017
title_sort depressive disorders in brazil: results from the global burden of disease study 2017
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526360/
https://www.ncbi.nlm.nih.gov/pubmed/32993670
http://dx.doi.org/10.1186/s12963-020-00204-5
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