Role of sex and high-fat diet in metabolic and hypothalamic disturbances in the 3xTg-AD mouse model of Alzheimer’s disease

BACKGROUND: Hypothalamic dysfunction occurs early in the clinical course of Alzheimer’s disease (AD), likely contributing to disturbances in feeding behavior and metabolic function that are often observed years prior to the onset of cognitive symptoms. Late-life weight loss and low BMI are associate...

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Detalles Bibliográficos
Autores principales: Robison, Lisa S., Gannon, Olivia J., Thomas, Melissa A., Salinero, Abigail E., Abi-Ghanem, Charly, Poitelon, Yannick, Belin, Sophie, Zuloaga, Kristen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526387/
https://www.ncbi.nlm.nih.gov/pubmed/32993686
http://dx.doi.org/10.1186/s12974-020-01956-5

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