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Phloretin ameliorates hepatic steatosis through regulation of lipogenesis and Sirt1/AMPK signaling in obese mice
BACKGROUND: Phloretin is isolated from apple trees and could increase lipolysis in 3T3-L1 adipocytes. Previous studies have found that phloretin could prevent obesity in mice. In this study, we investigated whether phloretin ameliorates non-alcoholic fatty liver disease (NAFLD) in high-fat diet (HFD...
Autores principales: | Liou, Chian-Jiun, Wu, Shu-Ju, Shen, Szu-Chuan, Chen, Li-Chen, Chen, Ya-Ling, Huang, Wen-Chung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526428/ https://www.ncbi.nlm.nih.gov/pubmed/33014333 http://dx.doi.org/10.1186/s13578-020-00477-1 |
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