Cargando…

Phloretin ameliorates hepatic steatosis through regulation of lipogenesis and Sirt1/AMPK signaling in obese mice

BACKGROUND: Phloretin is isolated from apple trees and could increase lipolysis in 3T3-L1 adipocytes. Previous studies have found that phloretin could prevent obesity in mice. In this study, we investigated whether phloretin ameliorates non-alcoholic fatty liver disease (NAFLD) in high-fat diet (HFD...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liou, Chian-Jiun, Wu, Shu-Ju, Shen, Szu-Chuan, Chen, Li-Chen, Chen, Ya-Ling, Huang, Wen-Chung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526428/ https://www.ncbi.nlm.nih.gov/pubmed/33014333 http://dx.doi.org/10.1186/s13578-020-00477-1

Ejemplares similares

Protective Effects of Licochalcone A Ameliorates Obesity and Non-Alcoholic Fatty Liver Disease Via Promotion of the Sirt-1/AMPK Pathway in Mice Fed a High-Fat Diet
por: Liou, Chian-Jiun, et al.
Publicado: (2019)

Phloretin Attenuates Allergic Airway Inflammation and Oxidative Stress in Asthmatic Mice
por: Huang, Wen-Chung, et al.
Publicado: (2017)

Corrigendum: Phloretin Attenuates Allergic Airway Inflammation and Oxidative Stress in Asthmatic Mice
por: Huang, Wen-Chung, et al.
Publicado: (2020)

IL-1 Signaling in Obesity-Induced Hepatic Lipogenesis and Steatosis
por: Negrin, Kimberly A., et al.
Publicado: (2014)

Flavonones from Penthorum chinense Ameliorate Hepatic Steatosis by Activating the SIRT1/AMPK Pathway in HepG2 Cells
por: Guo, Wei-Wei, et al.
Publicado: (2018)

Hepatic Proteomic Changes and Sirt1/AMPK Signaling Activation by Oxymatrine Treatment in Rats With Non-alcoholic Steatosis
por: Xu, Hong, et al.
Publicado: (2020)

Protective Effect of Isoliquiritigenin against Ethanol-Induced Hepatic Steatosis by Regulating the SIRT1-AMPK Pathway
por: Na, Ann-Yae, et al.
Publicado: (2018)

Trimetazidine improves hepatic lipogenesis and steatosis in non-alcoholic fatty liver disease via AMPK-ChREBP pathway
por: Zhang, Ying, et al.
Publicado: (2020)

Ginsenoside Rg3 ameliorates allergic airway inflammation and oxidative stress in mice
por: Huang, Wen-Chung, et al.
Publicado: (2021)

Fucoxanthin Ameliorates Oxidative Stress and Airway Inflammation in Tracheal Epithelial Cells and Asthmatic Mice
por: Wu, Shu-Ju, et al.
Publicado: (2021)

Tangshen Formula Alleviates Hepatic Steatosis by Inducing Autophagy Through the AMPK/SIRT1 Pathway
por: Wang, Yan, et al.
Publicado: (2019)

Nifedipine Modulates Renal Lipogenesis via the AMPK-SREBP Transcriptional Pathway
por: Lin, Yen-Chung, et al.
Publicado: (2019)

Clitorin ameliorates western diet-induced hepatic steatosis by regulating lipogenesis and fatty acid oxidation in vivo and in vitro
por: Cominguez, Divina C., et al.
Publicado: (2022)

Phloretin Ameliorates Succinate-Induced Liver Fibrosis by Regulating Hepatic Stellate Cells
por: Le, Cong Thuc, et al.
Publicado: (2023)

Loss of TDAG51 Results in Mature-Onset Obesity, Hepatic Steatosis, and Insulin Resistance by Regulating Lipogenesis
por: Basseri, Sana, et al.
Publicado: (2013)

MicroRNA-506-3p targets SIRT1 and suppresses AMPK pathway activation to promote hepatic steatosis
por: Hu, Liang-Kai, et al.
Publicado: (2021)

MicroRNA-506-3p targets SIRT1 and suppresses AMPK pathway activation to promote hepatic steatosis
por: Hu, Liang-Kai, et al.
Publicado: (2022)

Acacetin Protects against Non-Alcoholic Fatty Liver Disease by Regulating Lipid Accumulation and Inflammation in Mice
por: Liou, Chian-Jiun, et al.
Publicado: (2022)

Crocin ameliorates hepatic steatosis through activation of AMPK signaling in db/db mice
por: Luo, Li, et al.
Publicado: (2019)

Sema7A protects against high-fat diet-induced obesity and hepatic steatosis by regulating adipo/lipogenesis
por: Lu, Qiongyu, et al.
Publicado: (2023)

miR-122 promotes hepatic lipogenesis via inhibiting the LKB1/AMPK pathway by targeting Sirt1 in non-alcoholic fatty liver disease
por: Long, Jun-Ke, et al.
Publicado: (2019)

Zerumbone ameliorates high-fat diet-induced adiposity by restoring AMPK-regulated lipogenesis and microRNA-146b/SIRT1-mediated adipogenesis
por: Ahn, Jiyun, et al.
Publicado: (2017)

E3 ubiquitin ligase Grail promotes hepatic steatosis through Sirt1 inhibition
por: Liu, Pei-Yao, et al.
Publicado: (2021)

Fumigaclavine C ameliorates liver steatosis by attenuating hepatic de novo lipogenesis via modulation of the RhoA/ROCK signaling pathway
por: Yu, Wanguo, et al.
Publicado: (2023)

Miltefosine Suppresses Hepatic Steatosis by Activating AMPK Signal Pathway
por: Fang, Ru, et al.
Publicado: (2016)

Bitter melon extract attenuating hepatic steatosis may be mediated by FGF21 and AMPK/Sirt1 signaling in mice
por: Yu, Yongmei, et al.
Publicado: (2013)

l-Fucose ameliorates high-fat diet-induced obesity and hepatic steatosis in mice
por: Wu, Guangyan, et al.
Publicado: (2018)

Novel role of NLRP3-inflammasome in regulation of lipogenesis in fasting-induced hepatic steatosis
por: Liu, Baoqing, et al.
Publicado: (2019)

Metformin Ameliorates Hepatic Steatosis and Inflammation without Altering Adipose Phenotype in Diet-Induced Obesity
por: Woo, Shih-Lung, et al.
Publicado: (2014)

Inhibition of stearoyl-coenzyme A desaturase 1 ameliorates hepatic steatosis by inducing AMPK-mediated lipophagy
por: Zhou, Youping, et al.
Publicado: (2020)

Polyphenol-Rich Extracts from Toona sinensis Bark and Fruit Ameliorate Free Fatty Acid-Induced Lipogenesis through AMPK and LC3 Pathways
por: Chen, Yung-Chia, et al.
Publicado: (2019)

Amelioration of Hepatic Steatosis in Mice through Bacteroides uniformis CBA7346-Mediated Regulation of High-Fat Diet-Induced Insulin Resistance and Lipogenesis
por: Lee, Hye-Bin, et al.
Publicado: (2021)

P2Y2R Deficiency Ameliorates Hepatic Steatosis by Reducing Lipogenesis and Enhancing Fatty Acid β-Oxidation through AMPK and PGC-1α Induction in High-Fat Diet-Fed Mice
por: Dusabimana, Theodomir, et al.
Publicado: (2021)

Obeticholic acid ameliorates obesity and hepatic steatosis by activating brown fat
por: Zhang, Hanlin, et al.
Publicado: (2021)

Carvacrol Protects against Hepatic Steatosis in Mice Fed a High-Fat Diet by Enhancing SIRT1-AMPK Signaling
por: Kim, Eunkyung, et al.
Publicado: (2013)

Correction to: l-Fucose ameliorates high-fat diet-induced obesity and hepatic steatosis in mice
por: Wu, Guangyan, et al.
Publicado: (2020)

Hepatic steatosis risk is partly driven by increased de novo lipogenesis following carbohydrate consumption
por: Sanders, Francis W. B., et al.
Publicado: (2018)

MiR‐22 modulates the expression of lipogenesis‐related genes and promotes hepatic steatosis in vitro
por: Yang, Zhuo, et al.
Publicado: (2020)

Phloretin Modulates Human Th17/Treg Cell Differentiation In Vitro via AMPK Signaling
por: Jiao, Ao, et al.
Publicado: (2020)

Human hepatic lipase overexpression in mice induces hepatic steatosis and obesity through promoting hepatic lipogenesis and white adipose tissue lipolysis and fatty acid uptake
por: Cedó, Lídia, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_7kb7or6ojsrms7nfnfg7voc1ub