Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections

COVID-19–associated morbidity and mortality have been attributed to a pathologic host response. Two divergent hypotheses have been proposed: hyperinflammatory cytokine storm; and failure of host protective immunity that results in unrestrained viral dissemination and organ injury. A key explanation...

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Detalles Bibliográficos
Autores principales: Remy, Kenneth E., Mazer, Monty, Striker, David A., Ellebedy, Ali H., Walton, Andrew H., Unsinger, Jacqueline, Blood, Teresa M., Mudd, Philip A., Yi, Daehan J., Mannion, Daniel A., Osborne, Dale F., Martin, R. Scott, Anand, Nitin J., Bosanquet, James P., Blood, Jane, Drewry, Anne M., Caldwell, Charles C., Turnbull, Isaiah R., Brakenridge, Scott C., Moldwawer, Lyle L., Hotchkiss, Richard S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526441/
https://www.ncbi.nlm.nih.gov/pubmed/32687484
http://dx.doi.org/10.1172/jci.insight.140329

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