Local complement activation is associated with primary graft dysfunction after lung transplantation

BACKGROUND: The complement system plays a key role in host defense but is activated by ischemia/reperfusion injury (IRI). Primary graft dysfunction (PGD) is a form of acute lung injury occurring predominantly due to IRI, which worsens survival after lung transplantation (LTx). Local complement activ...

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Detalles Bibliográficos
Autores principales: Kulkarni, Hrishikesh S., Ramphal, Kristy, Ma, Lina, Brown, Melanie, Oyster, Michelle, Speckhart, Kaitlyn N., Takahashi, Tsuyoshi, Byers, Derek E., Porteous, Mary K., Kalman, Laurel, Hachem, Ramsey R., Rushefski, Melanie, McPhatter, Ja’Nia, Cano, Marlene, Kreisel, Daniel, Scavuzzo, Masina, Mittler, Brigitte, Cantu, Edward, Pilely, Katrine, Garred, Peter, Christie, Jason D., Atkinson, John P., Gelman, Andrew E., Diamond, Joshua M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Clinical Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526453/
https://www.ncbi.nlm.nih.gov/pubmed/32750037
http://dx.doi.org/10.1172/jci.insight.138358

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