Cargando…
Hydrogen-Rich Saline Regulates Microglial Phagocytosis and Restores Behavioral Deficits Following Hypoxia-Ischemia Injury in Neonatal Mice via the Akt Pathway
INTRODUCTION: We have reported previously that hydrogen-rich saline (HS) plays a neuroprotective role in hypoxia-ischemia (HI) brain damage in newborn mice. However, the mechanisms for this neuroprotection resulting from HS remain unknown. In this study, we examined the potential for HS to exert eff...
Autores principales: | Ke, Hongfei, Liu, Dexiang, Li, Tingting, Chu, Xili, Xin, Danqing, Han, Min, Wang, Shuanglian, Wang, Zhen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526477/ https://www.ncbi.nlm.nih.gov/pubmed/33061290 http://dx.doi.org/10.2147/DDDT.S264684 |
Ejemplares similares
-
Hydrogen-rich saline promotes microglia M2 polarization and complement-mediated synapse loss to restore behavioral deficits following hypoxia-ischemic in neonatal mice via AMPK activation
por: Chu, Xili, et al.
Publicado: (2019) -
L-Cysteine Provides Neuroprotection of Hypoxia-Ischemia Injury in Neonatal Mice via a PI3K/Akt-Dependent Mechanism
por: Li, Tingting, et al.
Publicado: (2021) -
BK Channel-Mediated Microglial Phagocytosis Alleviates Neurological Deficit After Ischemic Stroke
por: Huang, Shuxian, et al.
Publicado: (2021) -
CD22 blockade restores homeostatic microglial phagocytosis in aging brains
por: Pluvinage, John V., et al.
Publicado: (2019) -
Commentary: CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
por: Wei, Penghui, et al.
Publicado: (2019)