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Total Matrix Ca(2+) Modulates Ca(2+) Efflux via the Ca(2+)/H(+) Exchanger in Cardiac Mitochondria

Mitochondrial Ca(2+) handling is accomplished by balancing Ca(2+) uptake, primarily via the Ru360-sensitive mitochondrial calcium uniporter (MCU), Ca(2+) buffering in the matrix and Ca(2+) efflux mainly via Ca(2+) ion exchangers, such as the Na(+)/Ca(2+) exchanger (NCLX) and the Ca(2+)/H(+) exchange...

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Detalles Bibliográficos
Autores principales: Natarajan, Gayathri K., Glait, Lyall, Mishra, Jyotsna, Stowe, David F., Camara, Amadou K. S., Kwok, Wai-Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526510/
https://www.ncbi.nlm.nih.gov/pubmed/33041851
http://dx.doi.org/10.3389/fphys.2020.510600