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Total Matrix Ca(2+) Modulates Ca(2+) Efflux via the Ca(2+)/H(+) Exchanger in Cardiac Mitochondria
Mitochondrial Ca(2+) handling is accomplished by balancing Ca(2+) uptake, primarily via the Ru360-sensitive mitochondrial calcium uniporter (MCU), Ca(2+) buffering in the matrix and Ca(2+) efflux mainly via Ca(2+) ion exchangers, such as the Na(+)/Ca(2+) exchanger (NCLX) and the Ca(2+)/H(+) exchange...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526510/ https://www.ncbi.nlm.nih.gov/pubmed/33041851 http://dx.doi.org/10.3389/fphys.2020.510600 |