Cargando…
Total Matrix Ca(2+) Modulates Ca(2+) Efflux via the Ca(2+)/H(+) Exchanger in Cardiac Mitochondria
Mitochondrial Ca(2+) handling is accomplished by balancing Ca(2+) uptake, primarily via the Ru360-sensitive mitochondrial calcium uniporter (MCU), Ca(2+) buffering in the matrix and Ca(2+) efflux mainly via Ca(2+) ion exchangers, such as the Na(+)/Ca(2+) exchanger (NCLX) and the Ca(2+)/H(+) exchange...
Autores principales: | Natarajan, Gayathri K., Glait, Lyall, Mishra, Jyotsna, Stowe, David F., Camara, Amadou K. S., Kwok, Wai-Meng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526510/ https://www.ncbi.nlm.nih.gov/pubmed/33041851 http://dx.doi.org/10.3389/fphys.2020.510600 |
Ejemplares similares
-
Slow Ca(2+) Efflux by Ca(2+)/H(+) Exchange in Cardiac Mitochondria Is Modulated by Ca(2+) Re-uptake via MCU, Extra-Mitochondrial pH, and H(+) Pumping by F(O)F(1)-ATPase
por: Haumann, Johan, et al.
Publicado: (2019) -
LETM1: A Single Entity With Diverse Impact on Mitochondrial Metabolism and Cellular Signaling
por: Natarajan, Gayathri K., et al.
Publicado: (2021) -
Differential effects of buffer pH on Ca(2+)-induced ROS emission with inhibited mitochondrial complexes I and III
por: Lindsay, Daniel P., et al.
Publicado: (2015) -
Modeling Effects of L-Type Ca(2+) Current and Na(+)-Ca(2+) Exchanger on Ca(2+) Trigger Flux in Rabbit Myocytes with Realistic T-Tubule Geometries
por: Kekenes-Huskey, Peter M., et al.
Publicado: (2012) -
LETM1-Mediated K(+) and Na(+) Homeostasis Regulates Mitochondrial Ca(2+) Efflux
por: Austin, Shane, et al.
Publicado: (2017)