Cargando…

Amlodipine/valsartan fixed-dose combination treatment in the management of hypertension: A double-blind, randomized trial

To compare the fixed-dose combination (FDC) of amlodipine/valsartan 5/80 mg with valsartan 160 mg monotherapy for efficacy and safety in hypertensive patients. METHODS: We designed this double-blind, randomized, and noninferiority trial in which patients with elevated systolic blood pressure (SBP) a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Kang-Ling, Yu, Wen-Chung, Lu, Tse-Min, Chen, Lung-Ching, Leu, Hsin-Bang, Chiang, Chern-En
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526577/ https://www.ncbi.nlm.nih.gov/pubmed/33009241 http://dx.doi.org/10.1097/JCMA.0000000000000386

Ejemplares similares

Amlodipine and valsartan as components of a rational and effective fixed-dose combination
por: Waeber, Bernard, et al.
Publicado: (2009)

Efficacy of fixed-dose amlodipine and losartan combination compared with amlodipine monotherapy in stage 2 hypertension: a randomized, double blind, multicenter study
por: Kim, Sung H, et al.
Publicado: (2011)

Simultaneous Determination of Amlodipine and Valsartan
por: Mohamed, Nashwah Gadallah
Publicado: (2011)

Role of valsartan, amlodipine and hydrochlorothiazide fixed combination in blood pressure control: an update
por: Destro, Maurizio, et al.
Publicado: (2010)

Role of triple fixed combination valsartan, amlodipine and hydrochlorothiazide in controlling blood pressure
por: Doménech, Monica, et al.
Publicado: (2010)

Efficacy of amlodipine besylate and Valsartan for the treatment of mild to moderate hypertension
por: Wang, Xiao-ou, et al.
Publicado: (2019)

Addition of Amlodipine or Valsartan for Improvement of Diastolic Dysfunction Associated with Hypertension
por: Oh, Jin Kyung, et al.
Publicado: (2020)

The Fixed-Dose Combination of Olmesartan/Amlodipine Was Superior in Central Aortic Blood Pressure Reduction Compared with Perindopril/Amlodipine: A Randomized, Double-Blind Trial in Patients with Hypertension
por: Ruilope, Luis, et al.
Publicado: (2013)

A multicenter, randomized, and double-blind phase IV clinical trial to compare the efficacy and safety of fixed-dose combinations of amlodipine orotate/valsartan 5/160 mg versus valsartan/hydrochlorothiazide 160/12.5 mg in patients with essential hypertension uncontrolled by valsartan 160 mg monotherapy
por: Ahn, Youngkeun, et al.
Publicado: (2018)

Real-world effectiveness of amlodipine/valsartan and amlodipine/valsartan/hydrochlorothiazide in high-risk patients and other subgroups
por: Assaad-Khalil, Samir Helmy, et al.
Publicado: (2015)

Valsartan addition to amlodipine is more effective than losartan addition in hypertensive patients inadequately controlled by amlodipine
por: Fogari, Roberto, et al.
Publicado: (2010)

Erratum to: The Fixed-Dose Combination of Olmesartan/Amlodipine Was Superior in Central Aortic Blood Pressure Reduction Compared with Perindopril/Amlodipine: A Randomized, Double-Blind Trial in Patients with Hypertension
por: Ruilope, Luis, et al.
Publicado: (2014)

Erratum to: The Fixed-Dose Combination of Olmesartan/Amlodipine Was Superior in Central Aortic Blood Pressure Reduction Compared with Perindopril/Amlodipine: A Randomized, Double-Blind Trial in Patients with Hypertension
por: Ruilope, Luis, et al.
Publicado: (2015)

Exforge(®) (amlodipine/valsartan combination) in hypertension: the evidence of its therapeutic impact
por: Krzesinski, Jean-Marie, et al.
Publicado: (2010)

Pharmacokinetic and Safety Profiles of a Fixed‐Dose Combination of Amlodipine, Valsartan, and Atorvastatin: A 3‐Period Replicate Crossover Study
por: Kim, Seokuee, et al.
Publicado: (2019)

Efficacy and safety of two fixed-dose combinations of S-amlodipine and telmisartan (CKD-828) versus S-amlodipine monotherapy in patients with hypertension inadequately controlled using S-amlodipine monotherapy: an 8-week, multicenter, randomized, double-blind, Phase III clinical study
por: Ihm, Sang-Hyun, et al.
Publicado: (2016)

Cost-effectiveness of amlodipine compared with valsartan in preventing stroke and myocardial infarction among hypertensive patients in Taiwan
por: Chan, Lung, et al.
Publicado: (2016)

Triple combination therapy with amlodipine, valsartan, and hydrochlorothiazide vs dual combination therapy with amlodipine and hydrochlorothiazide for stage 2 hypertensive patients
por: Destro, Maurizio, et al.
Publicado: (2010)

Valsartan 160 mg/Amlodipine 5 mg Combination Therapy versus Amlodipine 10 mg in Hypertensive Patients with Inadequate Response to Amlodipine 5 mg Monotherapy
por: Sung, Jidong, et al.
Publicado: (2016)

A Review of the Efficacy and Tolerability of Combination Amlodipine/Valsartan in Non-White Patients with Hypertension
por: Ferdinand, Keith C., et al.
Publicado: (2013)

Effectiveness and safety of valsartan/amlodipine in hypertensive patients with stroke: China Status II subanalysis
por: Zhang, Weiliang, et al.
Publicado: (2017)

Comparative efficacy of generic nifedipine versus brand‐name amlodipine for hypertension management in Taiwan
por: Lee, Hao‐Wei, et al.
Publicado: (2022)

Extemporaneous Compounding and Physiological Modeling of Amlodipine/Valsartan Suspension
por: Aabed, Wafa' J., et al.
Publicado: (2021)

The combination of amlodipine/valsartan 5/160 mg produces less peripheral oedema than amlodipine 10 mg in hypertensive patients not adequately controlled with amlodipine 5 mg
por: Schrader, J, et al.
Publicado: (2009)

Clinical utility of fixed-dose combinations in hypertension: evidence for the potential of nebivolol/valsartan
por: Varagic, Jasmina, et al.
Publicado: (2014)

Efficacy and tolerability of fixed dose combination of metoprolol and amlodipine in Indian patients with essential hypertension
por: Rao, N. Srinivasa, et al.
Publicado: (2013)

Amlodipine/Valsartan (Avsar®): Efficacy in Hypertensive Patients - A Real World Observational Study (ALERT)
por: Khan, Khalid M, et al.
Publicado: (2020)

Effect of Amlodipine/Nebivolol combination therapy on central BP and PWV compared to Amlodipine/Valsartan combination therapy
por: Sultan, El-Zahraa M., et al.
Publicado: (2022)

A critical appraisal of the clinical effectiveness of a fixed combination of valsartan, amlodipine, and hydrochlorothiazide in achieving blood pressure goals
por: Laffer, Cheryl L, et al.
Publicado: (2011)

Clinical utility of fixed-combination telmisartan–amlodipine in the treatment of hypertension
por: Segura, Julian, et al.
Publicado: (2011)

Benefits of Valsartan and Amlodipine in Lipolysis through PU.1 Inhibition in Fructose-Induced Adiposity
por: Chou, Chu-Lin, et al.
Publicado: (2022)

Valsartan Improves Endothelial Dysfunction in Hypertension: A Randomized, Double-Blind Study
por: Tzemos, Nikolaos, et al.
Publicado: (2009)

In vitro and in vivo postmarketing surveillance of valsartan, alone or in combination with amlodipine or hydrochlorothiazide, among Palestinian hypertensive patients
por: Zaid, Abdel Naser, et al.
Publicado: (2016)

Leg edema with (S)-amlodipine vs conventional amlodipine given in triple therapy for hypertension: a randomized double blind controlled clinical trial
por: Galappatthy, Priyadarshani, et al.
Publicado: (2016)

Effect of hydrochlorothiazide in addition to telmisartan/amlodipine combination for treating hypertensive patients uncontrolled with telmisartan/amlodipine: a randomized, double-blind study
por: Higaki, Jitsuo, et al.
Publicado: (2016)

Comparison of Pharmacokinetics of a Fixed-Dose Combination of Amlodipine/Losartan/Rosuvastatin with Concomitant Administration of Amlodipine/Losartan and Rosuvastatin in Healthy Volunteers
por: Yoon, Deok Yong, et al.
Publicado: (2020)

To compare anti-albumin urea effects of valsartan alone with combination of valsartan and amlodipine in patients of chronic kidney disease
por: Ameen,, et al.
Publicado: (2016)

Efficacy and Safety of Valsartan/Amlodipine Single-Pill Combination in 11,422 Chinese Patients with Hypertension: an Observational Study
por: Hu, Dayi, et al.
Publicado: (2014)

Evaluation of effectiveness and safety of amlodipine/valsartan/hydrochlorothiazide single-pill combination therapy in hypertensive patients: an observational study
por: Hagendorff, Andreas, et al.
Publicado: (2014)

Effects of valsartan and amlodipine on oxidative stress in type 2 diabetic patients with hypertension: a randomized, multicenter study
por: Kim, Hae Jin, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_7pb0ift6u23844a9m03e3qeaek