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The effects of a Chinese herbal medicine (VGHBPH0) on patients with benign prostatic hyperplasia: A pilot study

The current Western medicine treatment options for benign prostatic hyperplasia (BPH) have various degrees of documented effectiveness. However, the uses of these interventions are limited to specific patient populations or have certain side effects that interfere with patient quality of life. This...

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Autores principales: Yeh, Hsin-Fu, Li, Tsai-Feng, Tsai, Cheng-Hung, Wu, Pei-Wen, Huang, Yi-Hsiu, Huang, William J., Chen, Fun-Jou, Hwang, Shinn-Jang, Chen, Fang-Pey, Wu, Ta-Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526580/
https://www.ncbi.nlm.nih.gov/pubmed/32649417
http://dx.doi.org/10.1097/JCMA.0000000000000384
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author Yeh, Hsin-Fu
Li, Tsai-Feng
Tsai, Cheng-Hung
Wu, Pei-Wen
Huang, Yi-Hsiu
Huang, William J.
Chen, Fun-Jou
Hwang, Shinn-Jang
Chen, Fang-Pey
Wu, Ta-Peng
author_facet Yeh, Hsin-Fu
Li, Tsai-Feng
Tsai, Cheng-Hung
Wu, Pei-Wen
Huang, Yi-Hsiu
Huang, William J.
Chen, Fun-Jou
Hwang, Shinn-Jang
Chen, Fang-Pey
Wu, Ta-Peng
author_sort Yeh, Hsin-Fu
collection PubMed
description The current Western medicine treatment options for benign prostatic hyperplasia (BPH) have various degrees of documented effectiveness. However, the uses of these interventions are limited to specific patient populations or have certain side effects that interfere with patient quality of life. This study evaluated the clinical effects of a Chinese herbal medicine (CHM) on patients with BPH. METHODS: This was a single-arm pilot study. Twenty BPH patients were enrolled, and they were required to take the investigated CHM three times a day for 8 weeks, along with their Western medicine. Patients returned to clinics as scheduled and completing international prostate symptoms scores (IPSS), aging male symptoms score, international index of erectile function, and body constitution questionnaire of traditional Chinese medicine. Uroflowmetry and sonography were also applied to evaluate the changes in urinary velocity and post-voiding residual urine volume from the baseline to the end of the study. RESULTS: The mean IPSS total score was significantly decreased by 2.5 points after 8 weeks of treatment with the CHM (from 17.5 to 15.0, p = 0.03). The mean IPSS voiding subscore was decreased by 1.7 points (from 10.1 to 8.4, p = 0.02), and the mean incomplete emptying subscore was decreased by 0.8 points (from 2.9 to 2.1, p = 0.02), with both decreases being statistically significant. A descending trend in the post-voiding residual urine volume was also observed (from 52.9 to 30.8 mL, p = 0.07). CONCLUSION: This trial indicated that the add-on CHM treatment (VGHBPH0) might be a potential treatment for improving the lower urinary tract symptoms of BPH patients.
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spelling pubmed-75265802020-10-14 The effects of a Chinese herbal medicine (VGHBPH0) on patients with benign prostatic hyperplasia: A pilot study Yeh, Hsin-Fu Li, Tsai-Feng Tsai, Cheng-Hung Wu, Pei-Wen Huang, Yi-Hsiu Huang, William J. Chen, Fun-Jou Hwang, Shinn-Jang Chen, Fang-Pey Wu, Ta-Peng J Chin Med Assoc Original Articles The current Western medicine treatment options for benign prostatic hyperplasia (BPH) have various degrees of documented effectiveness. However, the uses of these interventions are limited to specific patient populations or have certain side effects that interfere with patient quality of life. This study evaluated the clinical effects of a Chinese herbal medicine (CHM) on patients with BPH. METHODS: This was a single-arm pilot study. Twenty BPH patients were enrolled, and they were required to take the investigated CHM three times a day for 8 weeks, along with their Western medicine. Patients returned to clinics as scheduled and completing international prostate symptoms scores (IPSS), aging male symptoms score, international index of erectile function, and body constitution questionnaire of traditional Chinese medicine. Uroflowmetry and sonography were also applied to evaluate the changes in urinary velocity and post-voiding residual urine volume from the baseline to the end of the study. RESULTS: The mean IPSS total score was significantly decreased by 2.5 points after 8 weeks of treatment with the CHM (from 17.5 to 15.0, p = 0.03). The mean IPSS voiding subscore was decreased by 1.7 points (from 10.1 to 8.4, p = 0.02), and the mean incomplete emptying subscore was decreased by 0.8 points (from 2.9 to 2.1, p = 0.02), with both decreases being statistically significant. A descending trend in the post-voiding residual urine volume was also observed (from 52.9 to 30.8 mL, p = 0.07). CONCLUSION: This trial indicated that the add-on CHM treatment (VGHBPH0) might be a potential treatment for improving the lower urinary tract symptoms of BPH patients. Lippincott Williams & Wilkins 2020-07-02 2020-10 /pmc/articles/PMC7526580/ /pubmed/32649417 http://dx.doi.org/10.1097/JCMA.0000000000000384 Text en Copyright © 2020, the Chinese Medical Association. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Original Articles
Yeh, Hsin-Fu
Li, Tsai-Feng
Tsai, Cheng-Hung
Wu, Pei-Wen
Huang, Yi-Hsiu
Huang, William J.
Chen, Fun-Jou
Hwang, Shinn-Jang
Chen, Fang-Pey
Wu, Ta-Peng
The effects of a Chinese herbal medicine (VGHBPH0) on patients with benign prostatic hyperplasia: A pilot study
title The effects of a Chinese herbal medicine (VGHBPH0) on patients with benign prostatic hyperplasia: A pilot study
title_full The effects of a Chinese herbal medicine (VGHBPH0) on patients with benign prostatic hyperplasia: A pilot study
title_fullStr The effects of a Chinese herbal medicine (VGHBPH0) on patients with benign prostatic hyperplasia: A pilot study
title_full_unstemmed The effects of a Chinese herbal medicine (VGHBPH0) on patients with benign prostatic hyperplasia: A pilot study
title_short The effects of a Chinese herbal medicine (VGHBPH0) on patients with benign prostatic hyperplasia: A pilot study
title_sort effects of a chinese herbal medicine (vghbph0) on patients with benign prostatic hyperplasia: a pilot study
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526580/
https://www.ncbi.nlm.nih.gov/pubmed/32649417
http://dx.doi.org/10.1097/JCMA.0000000000000384
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