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Identification of Actionable Fusions as an Anti-EGFR Resistance Mechanism Using a Circulating Tumor DNA Assay
PURPOSE: Gene fusions are established oncogenic drivers and emerging therapeutic targets in advanced colorectal cancer. This study aimed to detail the frequencies and clinicopathological features of gene fusions in colorectal cancer using a circulating tumor DNA assay. METHODS: Circulating tumor DNA...
Autores principales: | Clifton, Katherine, Rich, Thereasa A., Parseghian, Christine, Raymond, Victoria M., Dasari, Arvind, Pereira, Allan Andresson Lima, Willis, Jason, Loree, Jonathan M., Bauer, Todd M., Chae, Young Kwang, Sherrill, Gary, Fanta, Paul, Grothey, Axel, Hendifar, Andrew, Henry, David, Mahadevan, Daruka, Nezami, Mohammad Amin, Tan, Benjamin, Wainberg, Zev A., Lanman, Richard, Kopetz, Scott, Morris, Van |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Clinical Oncology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526699/ https://www.ncbi.nlm.nih.gov/pubmed/33015522 http://dx.doi.org/10.1200/PO.19.00141 |
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